Acetamide,N-(4,5-dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)- (87-11-6)

Identification
Name:	Acetamide,N-(4,5-dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)-
Synonyms:	1,2-Dithiolo[4,3-b]pyrrol-5(4H)-one,6-acetamido-4-methyl- (6CI,7CI); 1,2-Dithiolo[4,3-b]pyrrole, acetamide deriv.;3-Acetamido-5-methylpyrrolin-4-one[4,3-d]-1,2-dithiole; Acetopyrrothin;N-(4,5-Dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)acetamide; NSC3927; Thiolutin
CAS:	87-11-6
Molecular Formula:	C8H8 N2 O2 S2
Molecular Weight:	228.30
InChI:	InChI=1/C8H8N2O2S2/c1-4(11)9-6-7-5(3-13-14-7)10(2)8(6)12/h3H,1-2H3,(H,9,11)
Molecular Structure:
Properties
Transport:	UN 2811 6.1/PG 2
Flash Point:	243.3°C
Boiling Point:	478.6°C at 760 mmHg
Density:	1.55g/cm³
Refractive index:	1.72
Biological Activity:	Antibiotic; inhibits bacterial RNA polymerase. Inhibits adhesion of HUVEC cells to vitronectin (IC 50 = 0.83 mM) and subsequently reduces paxillin levels. Suppresses tumor cell-induced angiogenesis.
Flash Point:	243.3°C
Storage Temperature:	−20°C
Safety Data
Hazard Symbols	T+: Very toxic T: Toxic