1H-Tetrazole-1-carboxamide,5-([1,1'-biphenyl]-4-ylmethyl)-N,N-dimethyl- (874902-19-9)

Identification
Name:	1H-Tetrazole-1-carboxamide,5-([1,1'-biphenyl]-4-ylmethyl)-N,N-dimethyl-
Synonyms:	LY 2183240
CAS:	874902-19-9
Molecular Formula:	C17H17 N5 O
Molecular Weight:	307.34978
InChI:	InChI=1/C17H17N5O/c1-21(2)17(23)22-16(18-19-20-22)12-13-8-10-15(11-9-13)14-6-4-3-5-7-14/h3-11H,12H2,1-2H3
Molecular Structure:
Properties
Density:	1.22g/cm³
Refractive index:	1.64
Biological Activity:	Novel and highly potent blocker of anandamide uptake (IC 50 = 270 pM). Inhibits fatty acid amide hydrolase (FAAH) activity (IC 50 = 12.4 nM). Following i.p. administration in rats, increases brain anandamide concentration and exerts antinociceptive effects in formalin model of pain.
Safety Data

Other Product

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