Phthalic acid (88-99-3)

The IUPAC name of this chemical is phthalic acid. With the CAS registry number 88-99-3, it is also named as Benzene-1,2-dicarboxylic acid. The product's categorie is Phthalic Acids, Esters and Derivatives. It is white crystals or fine white powder which is soluble in methanol and ethanol, slightly soluble in water and ether, insoluble in chloroform. In addition, this chemical is stable, combustible and incompatible with strong oxidizing agents. Furthermore, it should be sealed in the container.

The other characteristics of this product can be summarized as: (1)ACD/LogP: 0.88; (2)# of Rule of 5 Violations: 0; (3)ACD/BCF (pH 5.5): 1; (4)ACD/BCF (pH 7.4): 1; (5)ACD/KOC (pH 5.5): 1; (6)ACD/KOC (pH 7.4): 1; (7)#H bond acceptors: 4; (8)#H bond donors: 2; (9)#Freely Rotating Bonds: 2; (10)Index of Refraction: 1.618; (11)Molar Refractivity: 40.113 cm³; (12)Molar Volume: 114.493 cm³; (13)Polarizability: 15.902×10^-24 cm³; (14)Surface Tension: 70.304 dyne/cm; (15)Enthalpy of Vaporization: 66.051 kJ/mol; (16)Vapour Pressure: 0 mmHg at 25°C; (17)Rotatable Bond Count: 2; (18)Exact Mass: 166.026609; (19)MonoIsotopic Mass: 166.026609; (20)Topological Polar Surface Area: 74.6; (21)Heavy Atom Count: 12; (22)Complexity: 177.

Preparation of Phthalic acid: It can be obtained by the hydrolysis of phthalic anhydride. Adding phthalic anhydride to the 60 °C water, and stirring while adding ammonia to the ph value of 8. After bleaching filtered and acidified with hydrochloric acid, we can get the product by  washing. Reactive process:

Uses of Phthalic acid: It is used in the preparation of standard solution, dyes, polyester resin, polyester, plasticizers and drugs. And it is also used as analytical reagent. Furthermore, this chemical can react with 2-chloro-6-methyl-aniline to get N-(2-chloro-6-methyl-phenyl)-phthalimide. The temperature is 190 - 220 °C and the yield is 64%.

When you are using this chemical, please be cautious about it as the following:
It is irritating to eyes, respiratory system and skin. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. If you want to contact this product, you must wear suitable protective clothing, gloves and eye/face protection. 

People can use the following data to convert to the molecule structure. 
1. SMILES:c1ccc(c(c1)C(=O)O)C(=O)O
2. InChI:InChI=1/C8H6O4/c9-7(10)5-3-1-2-4-6(5)8(11)12/h1-4H,(H,9,10)(H,11,12)

The following are the toxicity data which has been tested.

The IUPAC name of this chemical is phthalic acid. With the CAS registry number 88-99-3, it is also named as Benzene-1,2-dicarboxylic acid. The product's categorie is Phthalic Acids, Esters and Derivatives. It is white crystals or fine white powder which is soluble in methanol and ethanol, slightly soluble in water and ether, insoluble in chloroform. In addition, this chemical is stable, combustible and incompatible with strong oxidizing agents. Furthermore, it should be sealed in the container.

The other characteristics of this product can be summarized as: (1)ACD/LogP: 0.88; (2)# of Rule of 5 Violations: 0; (3)ACD/BCF (pH 5.5): 1; (4)ACD/BCF (pH 7.4): 1; (5)ACD/KOC (pH 5.5): 1; (6)ACD/KOC (pH 7.4): 1; (7)#H bond acceptors: 4; (8)#H bond donors: 2; (9)#Freely Rotating Bonds: 2; (10)Index of Refraction: 1.618; (11)Molar Refractivity: 40.113 cm³; (12)Molar Volume: 114.493 cm³; (13)Polarizability: 15.902×10^-24 cm³; (14)Surface Tension: 70.304 dyne/cm; (15)Enthalpy of Vaporization: 66.051 kJ/mol; (16)Vapour Pressure: 0 mmHg at 25°C; (17)Rotatable Bond Count: 2; (18)Exact Mass: 166.026609; (19)MonoIsotopic Mass: 166.026609; (20)Topological Polar Surface Area: 74.6; (21)Heavy Atom Count: 12; (22)Complexity: 177.

Preparation of Phthalic acid: It can be obtained by the hydrolysis of phthalic anhydride. Adding phthalic anhydride to the 60 °C water, and stirring while adding ammonia to the ph value of 8. After bleaching filtered and acidified with hydrochloric acid, we can get the product by  washing. Reactive process:

Uses of Phthalic acid: It is used in the preparation of standard solution, dyes, polyester resin, polyester, plasticizers and drugs. And it is also used as analytical reagent. Furthermore, this chemical can react with 2-chloro-6-methyl-aniline to get N-(2-chloro-6-methyl-phenyl)-phthalimide. The temperature is 190 - 220 °C and the yield is 64%.

When you are using this chemical, please be cautious about it as the following:
It is irritating to eyes, respiratory system and skin. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. If you want to contact this product, you must wear suitable protective clothing, gloves and eye/face protection. 

People can use the following data to convert to the molecule structure. 
1. SMILES:c1ccc(c(c1)C(=O)O)C(=O)O
2. InChI:InChI=1/C8H6O4/c9-7(10)5-3-1-2-4-6(5)8(11)12/h1-4H,(H,9,10)(H,11,12)

The following are the toxicity data which has been tested.