| Identification | |
| Name: | 3,6-Acridinediamine |
| Synonyms: | Acridine,3,6-diamino- (8CI); 3,6-Diaminoacridine; 3,7-Diamino-5-azaanthracene; Isoflavbase; Proflavin; Proflavine |
| CAS: | 92-62-6 |
| EINECS: | 202-172-4 (Proflavine) |
| Molecular Formula: | C13H11 N3 |
| Molecular Weight: | 209.25 /225.29 |
| InChI: | InChI=1/C13H11N3/c14-9-4-5-12-8(6-9)7-10-11(15)2-1-3-13(10)16-12/h1-7H,14-15H2 |
| Molecular Structure: |  |
| Properties | |
| Transport: | 307 |
| Melting Point: | 260 C |
| Density: | 1.346 g/cm3 |
| Refractive index: | 1.833 |
| Water Solubility: | Slightly soluble SOLVENT |
| Solubility: | Slightly soluble SOLVENT |
| Appearance: | orange to brown powder |
| Specification: |
Proflavine (CAS NO.92-62-6), also called proflavin and diaminoacridine, is an acriflavine derivative, a disinfectant bacteriostatic against many gram-positive bacteria. Proflavine is also known to have a mutagenic effect on DNA by intercalating between nucleic acid base pairs. It differs from most other mutagenic components by causing basepair-deletions or basepair-insertions and not substitutions. Proflavine absorbs strongly in the blue region at 445nm (in water at pH 7) with molar extinction coefficient of c. 40,000. |
| Report: |
IARC Cancer Review: Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 24 (1980),p. 195.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program. |
| Color: | Yellow needles from alcohol. Solutions are brownish and when diluted are fluorescent. |
| Safety Data | |
| Hazard Symbols |
9 (Packing Group: III)
UN
NO.
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