| Identification | |
| Name: | Glimepiride |
| Synonyms: | 1h-pyrrole-1-carboxamide,2,5-dihydro-3-ethyl-4-methyl-n-(2-(4-(((((4-methylcyc; glimepirid; hoe490; trans-lohexyl)amino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-oxo; 1-[[p-[2-(3-ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido)ethyl]phenyl]sulfonyl]-3-(trans-4-methylcyclohexyl)urea; amary; AMARYL; Glimpiride |
| CAS: | 93479-97-1 |
| Molecular Formula: | C24H34N4O5S |
| Molecular Weight: | 490.62 |
| InChI: | InChI=1/C24H34N4O5S/c1-4-21-17(3)15-28(22(21)29)24(31)25-14-13-18-7-11-20(12-8-18)34(32,33)27-23(30)26-19-9-5-16(2)6-10-19/h7-8,11-12,16,19H,4-6,9-10,13-15H2,1-3H3,(H,25,31)(H2,26,27,30)/t16-,19- |
| Molecular Structure: |  |
| Properties | |
| Density: | 1.29 g/cm3 |
| Refractive index: | 1.599 |
| Water Solubility: | DMSO: >10 mg/mL |
| Solubility: | DMSO: >10 mg/mL |
| Appearance: | White Cyrstalline Solid |
| Specification: |
?Glimepiride , its cas register number is 93479-97-1. It also can be called 1-[[p-[2-(3-Ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido)ethyl]phenyl]sulfonyl]-3-(trans-4-methylcyclohexyl)urea ; Amary ; and Glista OD . It is the first third-generation sulfonylurea, and is very potent.?With Glimepiride (CAS NO.93479-97-1) GI absorption is complete, with no interference of meals. |
| Biological Activity: | Potent K ATP channel blocker and anti-diabetic agent. Inhibits pinacidil-activated cardiac K ATP channels with an IC 50 of 6.8 nM. |
| Storage Temperature: | Room temp |
| Color: | white |
| Usage: | A sulfonylurea hypoglycemic agent. Used as an antidiabetic |
| Safety Data | |
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