Identification |
Name: | BIX 01294, 2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine hydrate trihydrochloride |
Synonyms: | BIX 01294 hydrate trihydrochloride;BIX 01294, 2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine hydrate trihydrochloride |
CAS: | 935693-62-2 |
Molecular Formula: | C28H38N6O2.3ClH.H2O |
Molecular Weight: | 618.046 |
Molecular Structure: |
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Properties |
Biological Activity: | G9a-like protein and G9a histone lysine methyltransferase (HMTase) inhibitor (IC 50 values are 0.7 and 1.7 μ M respectively) that displays no activity at other HTMases up to 37 μ M. Modulates H3K9me2 levels in mammalian cells and potentiates induction of pluripotent stem cells from somatic cells in vitro . |
Storage Temperature: | 2-8°C |
Safety Data |
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