| Identification |
| Name: | 2-Furancarboxamide,5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)- |
| Synonyms: | 5-(4-Chlorophenyl)-furan-2-carboxylic acid 3,5-dimethoxyphenylamide;5-(4-Chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide;5-(4-Chlorophenyl)-N-(3,5-dimethoxyphenyl)-;5-(4-Chlorophenyl)-N-(3,5-dimethoxyphenyl)-2-furamide; |
| CAS: | 944261-79-4 |
| Molecular Formula: | C19H16ClNO4 |
| Molecular Weight: | 357.791 |
| InChI: | InChI=1/C19H16ClNO4/c1-23-15-9-14(10-16(11-15)24-2)21-19(22)18-8-7-17(25-18)12-3-5-13(20)6-4-12/h3-11H,1-2H3,(H,21,22) |
| Molecular Structure: |
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| Properties |
| Flash Point: | 226.3°C |
| Boiling Point: | 450.6°C at 760 mmHg |
| Density: | 1.294g/cm3 |
| Refractive index: | 1.611 |
| Biological Activity: | Selective blocker of Na V 1.8 channels (IC 50 values are 8, 2450, 6740, 7340 and 7380 nM for hNa V 1.8, hNa V 1.3, hNa V 1.7, hNa V 1.5 and hNa V 1.2 channels respectively). Shows no significant activity against TRPV1, P2X 2/3 , Ca V 2.2 and KCNQ2/3 channels. Antinociceptive; potently attenuates mechanical allodynia in two models of neuropathic pain following i.p. administration. |
| Flash Point: | 226.3°C |
| Safety Data |
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