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CROMAKALIM (94470-67-4)

Identification
Name:CROMAKALIM
Synonyms:AKOS 91890;(+/-)-CROMAKALIM;CROMAKALIM;TRANS-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-4-(2-OXO-1-PYRROLIDINYL)-2H-1-BENZOPYRAN-6-CARBONITRILE;(+/-)-TRANS-6-CYANO-3,4-DIHYDRO-2,2-DIMETHYL-4-(2-OXOPYRROLIDIN-1-YL)-2H-1-BENZOPYRAN-3-OL;[+/-]-TRANS-6-CYANO-3,4-DIHYDRO-2,2-DIMETHYL-4-[2-OXOPYRROLIDIN-1-YL]-2H-1-BENZOPYRAN-3-OL;Cromakalim=([+/-]-trans-6-Cyano-3,4-dihydro-2,2-;BRL-34915
CAS:94470-67-4
Molecular Formula: C16H18N2O3
Molecular Weight: 286.33
InChI: InChI=1/C16H18N2O3/c1-16(2)15(20)14(18-7-3-4-13(18)19)11-8-10(9-17)5-6-12(11)21-16/h5-6,8,14-15,20H,3-4,7H2,1-2H3
Molecular Structure: (C16H18N2O3) AKOS 91890;(+/-)-CROMAKALIM;CROMAKALIM;TRANS-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-4-(2-OXO-1-PYRROLIDI...
Properties
Flash Point: 245.5°C
Boiling Point: 482.3°C at 760 mmHg
Density:1.31g/cm3
Refractive index:1.615
Specification:
White Crystalline Solid
usageEng:Causes vasodilation by activation of potassim channels
Safety Statements:22-24/25
22:Do not breathe dust
24/25:Avoid contact with skin and eyes
Biological Activity: Prototypical K ATP channel opener. Relaxes rabbit isolated portal vein with an IC 50 value of 21 nM . Potent, orally active and hypotensive in vivo .
Flash Point: 245.5°C
Storage Temperature: 2-8°C
Usage:Causes vasodilation by activation of potassim channels
Safety Data
 

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