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Finasteride (98319-26-7)

Identification
Name:Finasteride
Synonyms:Proscar (TN);Finasteride (USP);Finpecia;4-Azaandrost-1-ene-17-carboxamide, N-(1,1-dimethylethyl)-3-oxo-, (5alpha,17beta)-;Proscar;Finastid;Propecia (TN);Propecia;MK-0906;MK 906;Finasteride [USAN:BAN:INN];MK-906;Prostide;Chibro-Proscar;Finasterida [INN-Spanish];Finasteridum [INN-Latin];N-tert-butyl-4-aza-5alpha-androsta-3-oxo-17beta-carboxamide;Finasteride 99%;
CAS:98319-26-7
Molecular Formula: C23H36N2O2
Molecular Weight: 372.55
InChI: InChI=1/C23H36N2O2/c1-21(2,3)25-20(27)17-8-7-15-14-6-9-18-23(5,13-11-19(26)24-18)16(14)10-12-22(15,17)4/h11,13-18H,6-10,12H2,1-5H3,(H,24,26)(H,25,27)/t14-,15-,16-,17+,18+,22-,23+/m0/s1
Molecular Structure: (C23H36N2O2) Proscar (TN);Finasteride (USP);Finpecia;4-Azaandrost-1-ene-17-carboxamide, N-(1,1-dimethylethyl)-3-o...
Properties
Transport:25kgs
Density:1.065 g/cm3
Refractive index:1.524
Water Solubility:insoluble
Solubility:DMSO: 32 mg/mL, soluble
Appearance:white to off-white crystalline powder
Specification:

?Finasteride , its cas register number 98319-26-7. It also can be called?N-(2-methyl-2-propyl)-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxamide ; Proscar ; N-tert-Butyl-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxamide ;?(5alpha,17beta)-(1,1-Dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide ; and 17beta-(N-tert-butylcarbamoyl)-4-aza-5 alpha-androst-1-en-3-one .?Its classification code are Drug / Therapeutic Agent;?Enzyme inhibitors;?Inhibitor [alpha reductase] and Reproductive Effect.
?Finasteride (marketed as Proscar, Propecia, Fincar, Finpecia, Finax, Finast, Finara, Finalo, Prosteride, Gefina, Appecia, Finasterid IVAX, Finasterid Alternova) is a synthetic antiandrogen which acts by inhibiting type II 5-alpha reductase, the enzyme that converts testosterone to dihydrotestosterone (DHT).
?Finasteride was approved initially in 1992 as Proscar, a treatment for prostate enlargement, but the sponsor had studied 1 mg of finasteride and demonstrated hair growth in male pattern hair loss. In 1997, the U.S. Food and Drug Administration approved finasteride to treat male pattern hair loss. Merck sells it under the brand name Propecia.
Health organisations and practising clinicians have expressed concerns that Propecia gives rise to persistent side effects in some men.

Color: White to off-white crystalline solid
Usage:

Inhibitor of 5a-reductase, the enzyme which converts testosterone to the more potent androgen, 5a-dihydrotestosterone. Antialopecia agent

Safety Data
Hazard Symbols T:Toxic
 

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