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Pyridine,2-chloro-6-(4-piperidinylthio)- (98330-05-3)

Identification
Name:Pyridine,2-chloro-6-(4-piperidinylthio)-
Synonyms:Anpirtoline
CAS:98330-05-3
Molecular Formula: C10H13 Cl N2 S
Molecular Weight: 228.7416
InChI: InChI=1/C10H13ClN2S.ClH/c11-9-2-1-3-10(13-9)14-8-4-6-12-7-5-8;/h1-3,8,12H,4-7H2;1H
Molecular Structure: (C10H13ClN2S) Anpirtoline
Properties
Flash Point: 174 ºC
Boiling Point: 364.1 ºC at 760 mmHg
Density:1.27 g/cm3
Biological Activity: Highly potent 5-HT 1B receptor agonist (K i values are 28, 150 and 1490 nM at 5-HT 1B , 5-HT 1A and 5-HT 2 receptors respectively). Decreases central serotonin synthesis and attenuates aggressive behavior in vivo . Also acts as an antagonist at 5-HT 3 receptors (K i = 29.5 nM) and is brain penetrant.
Flash Point: 174 ºC
Safety Data