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Ramipril

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[Fire Fighting]

Extinguish with carbon dioxide, dry chemical powder or appropriate foam. Water spray. Wear self-contained breathing apparatus and protective clothing to prevent contact with the skin and eyes.
[Storage]

Store in original container in a cool dark place.
[Inhalation]

Remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen. Seek medical attention.
[Skin]

Immediately wash skin with soap and copious amounts of water for at least 15 minutes. If irritation persists, seek medical attention.
[Eyes]

Immediately flush eyes with copious amounts of water for at least 15 minutes. Seek medical advice.
[Ingestion]

If swallowed, wash out mouth with water, provided person is conscious. Seek medical advice.
[Personal Protection]

Wear self-contained breathing apparatus, rubber boots & heavy rubber gloves.
[Solubility in water]

Insoluble
[Melting Point]

109
[Vapor Pressure]

4.9E-16 (25 C)
[Density]

1.20 g/cm3 (20 C)
[pKa/pKb]

3.17 (pKa)
[Partition Coefficient]

3.41
[Usage]

Long-acting angiotensin-converting enzyme inhibitor. It is a prodrug that is transformed in the liver to its active metabolite ramiprilat.
[Product Name]

Ramipril
[Synonyms]

(1S,5S,7S)-8-[(2S)-2-[[(1S)-1-Ethoxycarbonyl-3-phenyl-propyl]amino]propanoyl]-8-azabicyclo[3.3.0]octane-7-carboxylic acid
Cyclopenta(b)pyrrole-2-carboxylic acid, octahydro-1-(2-((1-(ethoxycarbonyl)-3-phenylpropyl) amino)-1-oxopropyl), (2S-(1(R*(R*)),2-alpha,3a-beta,6a-beta))
HOE-498
Ramipril
[CAS]

"CASEN_87333-19-5.htm">87333-19-5
[Formula]

C23H32N2O5
[Molecular Weight]

416.52
[RTECS]

GY5879600
[Merck]

12,8283
[Small spills/leaks]

Sweep-up/absorb in suitable material, place in a container and hold for disposal. Avoid raising dust. Ventilate area and wash spill site after pickup is complete.
[Combustion Products]

Emits toxic fumes under fire conditions.