[Fire Fighting] Extinguish with carbon dioxide, dry chemical powder or appropriate foam. Water spray. Wear self-contained breathing apparatus and protective clothing to prevent contact with the skin and eyes. | |
[Storage] Store in original container in a cool dark place. | |
[Inhalation] Remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen. Seek medical attention. | |
[Skin] Immediately wash skin with soap and copious amounts of water for at least 15 minutes. If irritation persists, seek medical attention. | |
[Eyes] Immediately flush eyes with copious amounts of water for at least 15 minutes. Seek medical advice. | |
[Ingestion] If swallowed, wash out mouth with water, provided person is conscious. Seek medical advice. | |
[Personal Protection] Wear self-contained breathing apparatus, rubber boots & heavy rubber gloves. | |
[Solubility in water] Insoluble | |
[Melting Point] 109 | |
[Vapor Pressure] 4.9E-16 (25 C) | |
[Density] 1.20 g/cm3 (20 C) | |
[pKa/pKb] 3.17 (pKa) | |
[Partition Coefficient] 3.41 | |
[Usage] Long-acting angiotensin-converting enzyme inhibitor. It is a prodrug that is transformed in the liver to its active metabolite ramiprilat. | |
[Product Name] Ramipril | |
[Synonyms] (1S,5S,7S)-8-[(2S)-2-[[(1S)-1-Ethoxycarbonyl-3-phenyl-propyl]amino]propanoyl]-8-azabicyclo[3.3.0]octane-7-carboxylic acid Cyclopenta(b)pyrrole-2-carboxylic acid, octahydro-1-(2-((1-(ethoxycarbonyl)-3-phenylpropyl) amino)-1-oxopropyl), (2S-(1(R*(R*)),2-alpha,3a-beta,6a-beta)) HOE-498 Ramipril | |
[CAS] "CASEN_87333-19-5.htm">87333-19-5 | |
[Formula] C23H32N2O5 | |
[Molecular Weight] 416.52 | |
[RTECS] GY5879600 | |
[Merck] 12,8283 | |
[Small spills/leaks] Sweep-up/absorb in suitable material, place in a container and hold for disposal. Avoid raising dust. Ventilate area and wash spill site after pickup is complete. | |
[Combustion Products] Emits toxic fumes under fire conditions. |