| [Fire Fighting] Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire. | |
| [Ingestion] Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended. | |
| [Inhalation] If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention. | |
| [Skin] Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse. | |
| [Eyes] If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention. | |
| [Storage] Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage. | |
| [Handling] All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood. | |
| [Inhalation] Hypoxemia and respiratory alkalosis has been observed following an acute overdose. | |
| [Ingestion] Gastrointestinal side effects include nausea (2% to 5%), vomiting (0.9%), diarrhea (3% to 13%), abdominal pain (17%), and constipation (0.6% to 2%). Nausea and abdominal cramping were reported in two overdose ingestions. | |
| [Personal Protection] Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots. | |
| [Respirators] Use NIOSH/MSHA approved respirator appropriate for exposure of concern. | |
| [Exposure Effects] Elevated body temperature, increased pulse, and increased respiratory rate may result from an acute overdose. therapeutic side effects have included headache, dizziness, fatigue, and malaise. Seizures are possible. Tremor was reported in one overdose. Women should be advised not to become pregnant while taking misoprostol. If pregnancy is suspected, use of the product should be discontinued and the pregnancy should be followed very closely (weekly) for the next 4 weeks. <br>Mobius' syndrome (congenital facial paralysis) were reported following maternal misoprostol administration. | |
| [Appearance] Light yellow oil. | |
| [Solubility in water] Insoluble | |
| [pKa/pKb] 13.92 (pKa) | |
| [Usage] Anti-ulcerative. | |
| [Product Name] (11alpha,13E)-(+)-11alpha,16-Dihydroxy-16-methyl-9-oxoprost-13E-en-1-oic acid methyl ester | |
| [Synonyms] Cytotec Methyl 7-[(1R,2R,3R)-3-hydroxy-2-[(E)-4-hydroxy-4-methyloct-1-enyl]-5-oxocyclopentyl]heptanoate Misoprostil Prost-13-en-1-oic acid, 11,16-dihydroxy-16-methyl-9-oxo-, methyl ester, (11a,13E)- | |
| [CAS] "CASEN_59122-46-2.htm">59122-46-2 | |
| [Formula] C22H38O5 | |
| [Molecular Weight] 382.54 | |
| [RTECS] UK8390000 | |
| [RTECS Class] Drug; Reproductive Effector; Human Data | |
| [Merck] 12,6297 | |
| [Beilstein/Gmelin] 4155643 | |
| [Small spills/leaks] Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces. | |
| [Stability] No data. | |
| [Incompatibilities] Strong oxidizing agents. |
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