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Propofol

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[Flash Point]

107
[Fire Fighting]

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
[Ingestion]

Get medical aid. Wash mouth out with water.
[Inhalation]

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
[Skin]

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
[Eyes]

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
[Storage]

Store in a cool, dry place. Store in a tightly closed container. Keep under an argon blanket. Refrigerator (approx 4 C).
[Handling]

Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing. Use only in a chemical fume hood.
[Ingestion]

Harmful if swallowed. May cause irritation of the digestive tract.
[Inhalation]

Dust is irritating to the respiratory tract. The toxicological properties of this substance have not been fully investigated.
[Skin]

Causes skin irritation.
[Eyes]

Causes eye irritation.
[EC Risk Phrase]

R 22 36/38
[EC Safety Phrase]

S 26 36/37/39
[UN (DOT)]

2810
[Personal Protection]

Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
[Respirators]

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
[Appearance]

Yellow-tan liquid.
[Solubility in water]

Insoluble
[Melting Point]

18
[Boiling Point]

256
[Vapor Pressure]

0.01 (25 C)
[Density]

1.032 g/cm3
[pKa/pKb]

11.00 (pKa)
[Partition Coefficient]

4.16
[Heat Of Vaporization]

51.3 kJ/mol
[Usage]

An intravenous sedative-hypnotic agent.
[Refractive Index]

1.5134 (20 C)
[Product Name]

Propofol
[Synonyms]

2,6-Bis(1-methylethyl)phenol
2,6-Bis(isopropyl)phenol
2,6-Diisopropylphenol
Diprofol
Disoprivan
Recofol
[CAS]

"CASEN_2078-54-8.htm">2078-54-8
[Formula]

C12H18O
[Molecular Weight]

178.27
[EINECS]

218-206-6
[RTECS]

SL0810000
[RTECS Class]

Drug; Reproductive Effector; Human Data
[Merck]

12,8020
[Beilstein/Gmelin]

1866484
[Beilstein Reference]

4-06-00-03435
[Small spills/leaks]

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container.
[Incompatibilities]

Oxidizing agents, bases, acid chlorides, acid anhydrides.
[Stability]

Stable under normal temperatures and pressures.
[Decomposition]

Carbon monoxide, carbon dioxide.
[UN Number]

2810