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DL-Thioctic acid

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[Flash Point]

173
[Fire Fighting]

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
[Ingestion]

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
[Inhalation]

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
[Skin]

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
[Eyes]

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
[Storage]

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
[Handling]

Wash thoroughly after handling. Use only in a well ventilated area. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
[Ingestion]

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.
[Inhalation]

May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
[Skin]

May cause skin irritation. The toxicological properties of this material have not been fully investigated.
[Eyes]

May cause eye irritation. The toxicological properties of this material have not been fully investigated.
[EC Risk Phrase]

R 22 36/37/38
[EC Safety Phrase]

S 26 36/37/39
[Personal Protection]

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
[Respirators]

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
[Appearance]

Light yellow to yellow powder.
[Solubility in water]

Very soluble
[Melting Point]

59 - 60
[Boiling Point]

363
[Vapor Pressure]

3E-6 (25 C)
[Density]

1.343 g/cm3
[pKa/pKb]

4.75 (pKa)
[Partition Coefficient]

2.16
[Heat Of Vaporization]

66.8 kJ/mol
[Usage]

L form is an essential cofactor for many enzyme complexes.
[Product Name]

5-(Dithiolan-3-yl)valeric acid
[Synonyms]

1,2-Dithiolane-3-pentanoic acid, (+/-)-
1,2-Dithiolane-3-valeric acid, (+/-)
5-(Dithiolan-3-yl)pentanoic acid
DL-1,2-Dithiolane-3-valeric acid
DL-6-Thioctic acid
DL-alpha-Lipoic acid
[CAS]

"CASEN_1077-28-7.htm">1077-28-7
[Formula]

C8H14O2S2
[Molecular Weight]

206.31
[EINECS]

214-071-2
[RTECS]

JP1192000
[RTECS Class]

Other
[Merck]

12,9462
[Beilstein/Gmelin]

81853
[Beilstein Reference]

5-19-07-00237
[Small spills/leaks]

Clean up spills immediately, using the appropriate protective equipment. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Provide ventilation.
[Incompatibilities]

Oxidizing agents.
[Stability]

Stable under normal temperatures and pressures.
[Decomposition]

Carbon monoxide, oxides of sulfur, carbon dioxide.