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Lomustine

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[Fire Fighting]

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.
[Ingestion]

Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
[Inhalation]

If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
[Skin]

Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
[Eyes]

Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.
[Storage]

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
[Handling]

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
[Inhalation]

Dose related pulmonary infiltration or fibrosis has been reported as a delayed adverse effect.
[Skin]

Skin irritation may occur.
[Ingestion]

Nausea and vomiting may occur.
[Personal Protection]

Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
[Respirators]

Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
[Exposure Effects]

CNS depression may occur. Use during pregnancy or while breast-feeding should be avoided.
[Appearance]

Yellow powder.
[Solubility in water]

practically insoluble
[Melting Point]

90
[Usage]

Medication.
[Product Name]

1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea
[Synonyms]

1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea
Belustine
N-(2-Chloroethyl)-N'-cyclohexyl-N-nitrosourea
[CAS]

"CASEN_13010-47-4.htm">13010-47-4
[Formula]

C9H16ClN3O2
[Molecular Weight]

233.7
[EINECS]

235-859-2
[RTECS]

YS4900000
[RTECS Class]

Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data
[Merck]

12,5594
[Beilstein/Gmelin]

2125058
[Small spills/leaks]

Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
[Stability]

No data.
[Incompatibilities]

Strong oxidizing agents.