Home >> msds >> Tegafur

Tegafur

Print        Favorite
[Fire Fighting]

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
[Ingestion]

Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
[Inhalation]

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration.
[Skin]

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
[Eyes]

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
[Storage]

Store in a tightly closed container. Store in a cool, dry area away from incompatible substances.
[Handling]

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Do not ingest or inhale.
[Ingestion]

May be harmful if swallowed. May cause encephalitis, muscular contractions, bone marrow depression, and neurological effects.
[Inhalation]

No information available.
[Skin]

May cause skin irritation.
[Eyes]

May cause eye irritation.
[Hazards]

During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
[Personal Protection]

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
[Respirators]

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
[Appearance]

White powder.
[Solubility in water]

Soluble
[Melting Point]

175
[Density]

1.52 g/cm3
[pKa/pKb]

8.66 (pKa)
[Product Name]

5-Fluoro-1-(tetrahydro-2-furanyl)-2,4(1H,3H)-pyrimidinedione
[Synonyms]

2,4(1H,3H)-Pyrimidinedione, 5-fluoro-1-(tetrahydro-2-furanyl)-
5-Fluoro-1-(2-tetrahydrofuranyl)uracil
Fluaid
N1-(2-Tetrahydrofuranyl)-5-fluorouracil
NSC 148958
Tegafur
[CAS]

"CASEN_17902-23-7.htm">17902-23-7
[Formula]

C8H9FN2O3
[Molecular Weight]

200.17
[EINECS]

241-846-2
[RTECS]

YR0450000
[RTECS Class]

Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data
[Merck]

12,9267
[Beilstein/Gmelin]

525766
[Beilstein Reference]

5-24-06-00285
[Small spills/leaks]

Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
[Stability]

Stable under normal temperatures and pressures.
[Incompatibilities]

Strong oxidizing agents.
[Decomposition]

Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, hydrogen fluoride.