| [Fire Fighting] Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam. | |
| [Fire Potential] This material is probably combustible. | |
| [Ingestion] If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. | |
| [Inhalation] Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. | |
| [Skin] Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Remove contaminated clothing and shoes. | |
| [Eyes] Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. | |
| [Storage] Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Deep freeze (below -20 C). | |
| [Handling] Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. | |
| [Inhalation] Inhalation of dust may cause respiratory tract irritation. | |
| [Skin] Causes skin irritation. | |
| [Eyes] Dust may cause mechanical irritation. | |
| [Ingestion] May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause blood abnormalities. | |
| [Personal Protection] Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. | |
| [Respirators] Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary. | |
| [Exposure Effects] May cause cancer in humans. | |
| [Appearance] White crystalline powder. | |
| [Solubility in water] Very soluble | |
| [Melting Point] 235 | |
| [Boiling Point] 478 | |
| [pKa/pKb] 13.69 (pKa) | |
| [Partition Coefficient] -1.8 | |
| [Usage] Used in the treatment of myelodysplastic syndrome. | |
| [Product Name] 5-Azacytidine | |
| [Synonyms] 1,3,5-Triazin-2(1H)-one, 4-amino-1-b-D-ribofuranosyl- Antibiotic U 18496 Azacytidine s-Triazin-2(1H)-one, 4-amino-1-b-D-ribofuranosyl- Vidaza | |
| [CAS] "CASEN_320-67-2.htm">320-67-2 | |
| [Formula] C8H12N4O5 | |
| [Molecular Weight] 244.21 | |
| [EINECS] 206-280-2 | |
| [RTECS] XZ3017500 | |
| [RTECS Class] Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data; Primary Irritant | |
| [Merck] 12,923 | |
| [Beilstein/Gmelin] 620461 | |
| [Small spills/leaks] Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation. | |
| [Stability] Stable under normal temperatures and pressures. | |
| [Incompatibilities] Strong oxidizing agents. | |
| [Decomposition] Carbon monoxide, oxides of nitrogen, carbon dioxide. |
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