| [Fire Fighting] Wear SCBA and full protective clothing. Extinguish fire with water, COT or dry chemical powder. | |
| [Ingestion] Seek immediate medial attention. | |
| [Inhalation] Seek immediate medial attention. | |
| [Skin] Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. | |
| [Eyes] Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility. | |
| [Storage] Store under refrigeration, in orginal container. | |
| [Handling] All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood. | |
| [Inhalation] Dyspnea, acute bronchospasm, apnea and cyanosis have been reported. Fatal pulmonary toxicity has been reported after oral use. | |
| [Skin] Rash, urticaria and/or pruritus have been infrequently reported. Erythema and desquamation, alopecia, onycholysis, and stevens-johnson syndrome have occurred following therapeutic use of etoposide. | |
| [Eyes] Conjunctivitis. | |
| [Ingestion] Ausea, vomiting and diarrhea commonly occur. Paralytic ileus has been reported. | |
| [Personal Protection] Surgical latex gloves -- which should be changed regularly. Safety goggles. | |
| [Respirators] Use NIOSH/MSHA approved respirator appropriate for exposure of concern. | |
| [Exposure Effects] Bone marrow supression. Cytotoxic agent. Anaphlactic-like reaction is possible. Possible carcinogen. | |
| [Appearance] Typically in the form of pink, liquid fillled, soft gelatin capsules. | |
| [Solubility in water] approx 0.08 mg/ml | |
| [Melting Point] 262 - 263 | |
| [Usage] Medication. | |
| [Product Name] Etoposide | |
| [Synonyms] (-)-Etoposide, (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside 4'-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-beta-D-glucopyranoside) 9-((4,6-O-Ethylidene-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one Lastet Toposar VePesid | |
| [CAS] "CASEN_33419-42-0.htm">33419-42-0 | |
| [Formula] C29H32O13 | |
| [Molecular Weight] 588.57000000000005 | |
| [EINECS] 251-509-1 | |
| [RTECS] KC0190000 | |
| [RTECS Class] Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data | |
| [Merck] 12,3931 | |
| [Beilstein/Gmelin] 3659695 | |
| [Small spills/leaks] Scoop up material and place in container for later disposal. | |
| [Stability] Stable under normal storage and usage conditions. Avoid elevated temperatures. |
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