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Histamine

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[Fire Fighting]

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
[Ingestion]

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
[Inhalation]

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
[Skin]

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
[Eyes]

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
[Storage]

Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Refrigerator (approx 4 C). Store protected from light.
[Handling]

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
[Inhalation]

May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
[Skin]

May cause skin irritation. The toxicological properties of this material have not been fully investigated.
[Eyes]

May cause eye irritation. The toxicological properties of this material have not been fully investigated.
[Ingestion]

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.
[Personal Protection]

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
[Respirators]

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use. Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
[Exposure Effects]

The toxicological properties of this material have not been investigated.
[Appearance]

Yellow crystals.
[Solubility in water]

Very soluble
[Melting Point]

147.85 - 149.85
[Boiling Point]

167 (0.8 torr)
[pKa/pKb]

10.15 (pKa)
[Usage]

Medication.
[Product Name]

4-(2-Aminoethyl)-1H-imidazole
[Synonyms]

1H-Imidazole-4-ethanamine
2-(4-Imidazolyl)ethanamine
2-Imidazol-4-ylethylamine
5-Imidazoleethylamine
Ergamine
Ergotidine
[CAS]

"CASEN_51-45-6.htm">51-45-6
[Formula]

C5H9N3
[Molecular Weight]

111.15
[EINECS]

200-100-6
[RTECS]

MS1050000
[RTECS Class]

Mutagen; Reproductive Effector; Natural Product
[Merck]

12,4756
[Beilstein/Gmelin]

2012
[Beilstein Reference]

4-25-00-02049
[Small spills/leaks]

Clean up spills immediately, using the appropriate protective equipment. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Provide ventilation.
[Incompatibilities]

Oxidizing agents.
[Stability]

Stable under normal temperatures and pressures.
[Decomposition]

Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitric oxide (NOx) and ammonia (NH3) fumes, nitrogen.