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Propylthiouracil

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[Fire Fighting]

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire.
[Ingestion]

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately.
[Inhalation]

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
[Skin]

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Remove contaminated clothing and shoes.
[Eyes]

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
[Storage]

Store in a cool, dry place. Keep container closed when not in use. Hormones and antibiotics room.
[Handling]

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
[Ingestion]

See inhalation.
[Inhalation]

Symptoms of exposure to this compound include recurrent painful skin lesions, fatigue, migratory polyanthralgias of hands and knees, palpable spleen, splenomegaly, amenorrhea, low-grade fever, gingivostomatitis, weakness, weight loss, dark red-brown colored urine, necrotizing vasculitis, leukopenia, cutaneous vasculitis, nasal congestion, enlarged thyroid, necrotic ulcerations on the lower extremities, bloody nasal discharge and cough.
[Skin]

Skin rashes may occur secondary to hematologic toxicity during chronic therapy.
[Eyes]

See inhalation
[EC Risk Phrase]

R 22
[EC Safety Phrase]

S 24/25
[Personal Protection]

Eyes: Wear chemical goggles. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
[Respirators]

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
[Appearance]

Odorless white crystalline powder of starch-like appearance. Bitter taste. Saturated solution is neutral or slightly acid to litmus.
[Solubility in water]

Slightly soluble
[Melting Point]

215 - 218
[Boiling Point]

448
[Vapor Pressure]

0.54 (25 C)
[pKa/pKb]

7.63 (pKa)
[Partition Coefficient]

1.37
[Usage]

Medication.
[Product Name]

2-Mercapto-6-propylpyrimid-4-one
[Synonyms]

2,3-Dihydro-6-propyl-2-thioxo-4(1h)pyrimidinone
2-Mercapto-4-hydroxy-6-n-propylpyrimidine
2-Mercapto-6-propylpyrimid-4-one
Procasil
Propacil
Propycil
[CAS]

"CASEN_51-52-5.htm">51-52-5
[Formula]

C7H10N2OS
[Molecular Weight]

170.23
[EINECS]

200-103-2
[RTECS]

YR1400000
[RTECS Class]

Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data
[Merck]

12,8054
[Beilstein/Gmelin]

130039
[Beilstein Reference]

5-24-07-00257
[EC Class]

harmful
[Small spills/leaks]

Clean up spills immediately, using the appropriate protective equipment.
[Incompatibilities]

Incompatible with strong oxidizing agents, strong acids and strong bases Reacts with sulfhydryl-oxidizing agents.
[Stability]

Stable under normal temperatures and pressures.
[Decomposition]

Irritating and toxic fumes and gases.
[HS Code]

2933 59 95