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Histamine dihydrochloride

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[Fire Fighting]

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
[Ingestion]

Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
[Inhalation]

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
[Skin]

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
[Eyes]

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
[Storage]

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
[Handling]

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation.
[Inhalation]

Causes respiratory tract irritation. May cause allergic respiratory reaction. May cause effects similar to those described for ingestion. Can produce delayed pulmonary edema. May cause respiratory sensitization.
[Skin]

Causes skin irritation. May cause an allergic reaction in certain individuals. May cause sensitization by skin contact.
[Eyes]

Causes eye irritation. May cause chemical conjunctivitis.
[Ingestion]

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause flushing followed by pallor, dizziness, fainting, fall in blood pressure, headache, rapid weak pulse, pain, and itching.
[EC Risk Phrase]

R 36/37/38 42/43
[EC Safety Phrase]

S 22 26 36/37/39 45
[UN (DOT)]

3335
[Personal Protection]

Eyes: Wear safety glasses and chemical goggles if splashing is possible. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
[Respirators]

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
[Exposure Effects]

Effects may be delayed.
[Appearance]

White crystals.
[Melting Point]

246
[Density]

1.43 g/cm3
[Usage]

Histamine is involved in local immune responses, regulating physiological function in the gut and as a neurotransmitter.
[Product Name]

2-(4-Imidazolyl)ethylamine dihydrochloride
[Synonyms]

2-(3H-Imidazol-4-yl)ethanamine dihydrochloride
Ceplene
Histamine dihydrochloride
Peremin
[CAS]

"CASEN_56-92-8.htm">56-92-8
[Formula]

C5H11Cl2N3
[Molecular Weight]

184.06
[EINECS]

200-298-4
[RTECS]

MS1575000
[RTECS Class]

Drug; Reproductive Effector
[Merck]

13,4739
[Beilstein/Gmelin]

3624116
[Beilstein Reference]

4-25-00-02049
[Small spills/leaks]

Wash area with soap and water. Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
[Stability]

Stable under normal temperatures and pressures.
[Incompatibilities]

Strong oxidizing agents.
[Decomposition]

Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide.
[UN Number]

3335