| [Fire Fighting] Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam. Use agent most appropriate to extinguish fire. | |
| [Fire Potential] Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. | |
| [Ingestion] Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. | |
| [Inhalation] Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask. | |
| [Skin] Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. | |
| [Eyes] Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. | |
| [Storage] Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Refrigerator (approx 4 C). | |
| [Handling] Wash thoroughly after handling. Minimize dust generation and accumulation. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale. Use only in a chemical fume hood. Wash clothing before reuse. | |
| [Inhalation] May be fatal if inhaled. May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. | |
| [Skin] May cause skin irritation. May be fatal if absorbed through the skin. | |
| [Eyes] May cause eye irritation. | |
| [Ingestion] May be fatal if swallowed. May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated. | |
| [Hazards] Contact with metals may evolve flammable hydrogen gas. | |
| [UN (DOT)] 2811 | |
| [Personal Protection] Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. | |
| [Respirators] A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use. | |
| [Exposure Effects] Prolonged exposure may cause non-specific nervous system effects. Prolonged or repeated exposure may cause convulsions. | |
| [Appearance] Light yellow powder. | |
| [Solubility in water] Insoluble | |
| [Melting Point] 234 - 235 | |
| [pKa/pKb] 7.24 (pKb) | |
| [Product Name] (R-(R*,S*))-6-(5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-furo(3,4-e)-1,3-benzodioxol-8(6H)-one | |
| [Synonyms] (+)-Bicuculline (6R)-6-[(5S)-6-Methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-6H-furo[4,3-g][1,3]benzodioxol-8-one 1,3-Dioxolo[4,5-g]isoquinoline, furo[3,4-e]-1,3-benzodioxol-8(6H)-one deriv. Bicuculline D-Bicuculline Furo(3,4-e)-1,3-benzodioxol-8(6H)-one, 6-(5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo(4,5-g) isoquinolin-5-yl)-, (R-(R*,S*))- | |
| [CAS] "CASEN_485-49-4.htm">485-49-4 | |
| [Formula] C20H17NO6 | |
| [Molecular Weight] 367.35 | |
| [EINECS] 207-619-7 | |
| [RTECS] LV0909840 | |
| [RTECS Class] Agricultural Chemical and Pesticide; Natural Product | |
| [Merck] 12,1250 | |
| [Beilstein/Gmelin] 98786 | |
| [Beilstein Reference] 4-27-00-06900 | |
| [Small spills/leaks] Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation. | |
| [Stability] No data. | |
| [Incompatibilities] Strong oxidizing agents, strong bases. | |
| [Decomposition] Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide. | |
| [Combustion Products] Fire may produce irritating, corrosive and/or toxic gases. | |
| [UN Number] 2811 | |
| [Hazard Class] 6.1 | |
| [Packing Group] I; II; III |
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