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2,4,6-Trimethylphenol

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[Fire Fighting]

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. In case of fire use water spray, dry chemical, carbon dioxide, or chemical foam.
[Fire Potential]

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
[Ingestion]

Dilution - may enhance absorption of phenol, and should be avoided. Ipecac induced vomiting is not recommended because of the potential for cns depression and seizures. Activated charcoal - may limit systemic toxicity if administered soon after ingestion, but may interfere with endoscopic evaluation of gastrointestinal burns.
[Inhalation]

Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
[Skin]

Remove phenol with undiluted polyethylene glycol 300 to 400 or isopropyl alcohol prior to washing, if readily available. Wash exposed areas twice with large quantities of water. A physician may need to examine the exposed area if irritation or pain persist after the area is washed.
[Eyes]

Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.
[Storage]

Store in a cool, dry place. Store in a tightly closed container. Corrosives area.
[Handling]

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
[Inhalation]

Tachypnea is commonly reported; pulmonary edema and bronchospasm may also occur. Stridor has been reported from exposure to high concentrations of phenol. Respiratory arrest occurred 30 minutes post ingestion of 26.7 Grams of phenol in one case.
[Skin]

Phenol is corrosive to the skin, but because of anesthetic qualities, it will numb rather than causing a burning pain on contact. Skin becomes red and swollen, then white and opaque. Deep burns result that may become gangrenous.
[Eyes]

Causes burns.
[Ingestion]

Phenol is extremely corrosive and may cause oral and esophageal burns and abdominal pain following ingestion.
[Hazards]

Contact with metals may evolve flammable hydrogen gas.
[EC Risk Phrase]

R 34
[EC Safety Phrase]

S 26 36/37/39 45
[UN (DOT)]

1759
[Personal Protection]

Organic canister mask; face shield; rubber gloves; other protective clothing to prevent contact with skin. In fire conditions, wear goggles and self contained breathing apparatus. Wear appropriate chemical protective gloves, boots and goggles.
[Respirators]

Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Wear appropriate protective clothing and gloves to prevent skin exposure.
[Exposure Effects]

Abnormally low blood pressure, reduced body temperature, rapid breathing, and rapid heart rate may develop with severe toxicity. Initial CNS excitation, including seizures, is commonly followed by CNS depression ranging from lethargy to coma and death. Fetotoxicity and skeletal abnormalities have been reported in animal experiments.
[Appearance]

White to beige, crystalline powder.
[Solubility in water]

1.01 g/L at 25 C
[Melting Point]

74
[Boiling Point]

56 (0.1 torr)
[Vapor Pressure]

.05
[Density]

1.046 g/cm3 (20 C)
[pKa/pKb]

10.88 (pKa)
[Partition Coefficient]

2.73
[Usage]

Chemical intermediate for poly(2,6-dimethyl-1,4-phenylene oxide) & its phosphate ester.
[Product Name]

2,4,6-Trimethylphenol
[Synonyms]

1-Hydroxy-2,4,6-trimethylbenzene
2-Hydroxymesitylene
Benzene, 2-hydroxy-1,3,5-trimethyl
Mesitol
Mesityl alcohol
Phenol, 2,4,6-trimethyl
[CAS]

"CASEN_527-60-6.htm">527-60-6
[Formula]

C9H12O
[Molecular Weight]

136.21
[EINECS]

208-419-2
[RTECS]

OX6590000
[RTECS Class]

Other
[Beilstein/Gmelin]

1859675
[Beilstein Reference]

4-06-00-03253
[Small spills/leaks]

Vacuum or sweep up material and place into a suitable disposal container.
[Incompatibilities]

Bases, acid chlorides, oxidizing agents, copper, copper alloys, brass, steel, acid anhydrides.
[Stability]

No data.
[Decomposition]

Carbon monoxide, carbon dioxide.
[Combustion Products]

Fire may produce irritating, corrosive and/or toxic gases.
[UN Number]

1759
[Hazard Class]

8
[Packing Group]

I; II; III