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Formestane

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[Fire Fighting]

Extinguish with carbon dioxide, dry chemical powder or appropriate foam. Water spray. Wear self-contained breathing apparatus and protective clothing to prevent contact with the skin and eyes.
[Ingestion]

If swallowed, wash out mouth with water, provided person is conscious. Seek medical advice.
[Inhalation]

Remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen. Seek medical attention.
[Skin]

Immediately wash skin with soap and copious amounts of water for at least 15 minutes. If irritation persists, seek medical attention.
[Eyes]

Immediately flush eyes with copious amounts of water for at least 15 minutes. Seek medical advice.
[Storage]

Store cool, dark and dry.
[EC Risk Phrase]

R: 20/21/22
[EC Safety Phrase]

S: 36/37
[Personal Protection]

Wear self-contained breathing apparatus, rubber boots & heavy rubber gloves.
[Exposure Effects]

Harmful by inhalation, in contact with skin and if swallowed.
[Appearance]

White powder.
[Solubility in water]

Insoluble
[Melting Point]

199 - 202
[Vapor Pressure]

4.9E-11 (25 C)
[Density]

1.19 g/cm3 (20 C)
[pKa/pKb]

9.31 (pKa)
[Partition Coefficient]

2.66
[Usage]

Used in the treatment of estrogen-receptor positive breast cancer in post-menopausal women.
[Product Name]

Formestane
[Synonyms]

4-Hydroxy-4-androstene-3,17-dione
4-Hydroxy-delta(sub 4)-androstenedione
CGP-32349
[CAS]

"CASEN_566-48-3.htm">566-48-3
[Formula]

C19H26O3
[Molecular Weight]

302.41000000000003
[RTECS]

BV8152500
[Merck]

12,4267
[Beilstein/Gmelin]

1889793
[Small spills/leaks]

Sweep-up/absorb in suitable material, place in a container and hold for disposal. Avoid raising dust. Ventilate area and wash spill site after pickup is complete.
[Combustion Products]

Emits toxic fumes under fire conditions.