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Sulindac

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[Flash Point]

306
[Fire Fighting]

Extinguish using Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
[Ingestion]

If swallowed, wash out mouth with water provided person is conscious. Call a physician.
[Inhalation]

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
[Skin]

In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
[Eyes]

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.
[Storage]

Keep tightly closed.
[Inhalation]

May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
[Skin]

May cause skin irritation. May be harmful if absorbed through the skin.
[Eyes]

May cause eye irritation.
[Ingestion]

Harmful if swallowed.
[Hazards]

Emits toxic fumes under fire conditions.
[EC Risk Phrase]

22
[Personal Protection]

Compatible chemical-resistant gloves. Chemical safety goggles.
[Respirators]

Government approved respirator.
[Exposure Effects]

Toxic if swallowed. Target organ(s): Liver. G.I. System.
[Solubility in water]

Insoluble
[Melting Point]

195
[Boiling Point]

582
[Vapor Pressure]

2E-14 (25 C)
[pKa/pKb]

4.22 (pKa)
[Partition Coefficient]

3.42
[Heat Of Vaporization]

91.5 kJ/mol
[Usage]

Nonsteroidal anti-inflammatory; preferential inhibitor of cox-1.
[Product Name]

Sulindac
[Synonyms]

(Z)-5-Fluoro-2-methyl-1-[p-(methylsulfinyl)benzylidene]indene-3-acetic acid
5-Fluoro-2-methyl-1-[[4-(methylsulfinyl)phenyl]methylene]-1H-indene-3-acetic acid
cis-5-Fluoro-2-methyl-1-[(p-methylsulfinyl)benzylidenyl]indene-3-acetic acid
[CAS]

"CASEN_38194-50-2.htm">38194-50-2
[Formula]

C20H17FO3S
[Molecular Weight]

356.42
[EINECS]

253-819-2
[RTECS]

NK8226000
[RTECS Class]

Drug; Reproductive Effector; Human Data
[Merck]

12,9155
[Beilstein/Gmelin]

2951842
[Beilstein Reference]

6-10
[Small spills/leaks]

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
[Stability]

Stable at normal temperatures and pressures.
[Incompatibilities]

Strong oxidizing agents.
[Decomposition]

Carbon monoxide, Carbon dioxide, Sulfur oxides, Hydrogen fluoride.