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Triamcinolone acetonide

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[Flash Point]

145
[Flash Point]

303
[Fire Fighting]

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
[Fire Fighting]

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.
[Ingestion]

Get medical aid. Wash mouth out with water.
[Ingestion]

If swallowed, wash out mouth with water provided person is conscious. Call a physician.
[Inhalation]

If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
[Inhalation]

Causes respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
[Inhalation]

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
[Skin]

Causes skin irritation.
[Skin]

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
[Skin]

In case of contact, immediately wash skin with soap and copious amounts of water.
[Eyes]

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
[Eyes]

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.
[Eyes]

Causes eye irritation.
[Storage]

Keep tightly closed.
[Storage]

Store in a cool, dry place. Store in a tightly closed container.
[Handling]

Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
[Ingestion]

May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
[Inhalation]

May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
[Skin]

May cause skin irritation. May be harmful if absorbed through the skin.
[Eyes]

May cause eye irritation.
[Ingestion]

May be harmful if swallowed.
[Hazards]

Emits toxic fumes under fire conditions.
[EC Risk Phrase]

R 36/37/38
[EC Safety Phrase]

S 26 36
[EC Safety Phrase]

22 24/25
[Personal Protection]

Protective gloves. Chemical safety goggles.
[Personal Protection]

Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
[Respirators]

Wear dust mask.
[Respirators]

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
[Exposure Effects]

Avoid contact and inhalation. Target organ(s): Endocrine system.
[Appearance]

Beige - light brown powder.
[Solubility in water]

Insoluble
[Solubility in water]

Very soluble
[Melting Point]

274
[Boiling Point]

317
[Boiling Point]

577
[Vapor Pressure]

0.0002 (25 C)
[Vapor Pressure]

1E-15 (25 C)
[pKa/pKb]

2.08 (pKa)
[pKa/pKb]

12.69 (pKs)
[Partition Coefficient]

1.67
[Heat Of Vaporization]

58.9 kJ/mol
[Heat Of Vaporization]

99.2 kJ/mol
[Usage]

A synthetic corticosteroid. Used for replacement therapy in people whose adrenal glands are not producing enough natural steroids (adrenal insufficiency) and decreasing inflammation in certain disease states. .
[Usage]

Metabolic antagonist.
[Product Name]

9a-Fluoro-11b,16a,17a,21-tetrahydroxy-1,4-pregnadiene-3,20-dione 16,17-acetonide
[Synonyms]

2-Amino-5-methylbenzoic acid
2-Carboxy-4-methylaniline
5-Methyl-2-aminobenzoic acid
5-Methylanthranilic acid
9a-Fluoro-11b,16a,17a,21-tetrahydroxy-1,4-pregnadiene-3,20-dione 16,17-acetonide
9-a-fluoro-11-b,21-dihydroxy-16-a,17-a-isopropylidenedioxypregna-1,4-diene-3,20-dione
9a-Fluoro-16a,17a-isopropylidenedihydroxyprednisolone
9a-Fluoro-16a-hydroxyprednisolone 16a,17a-acetonide
Kenalog
Polcortoon
[CAS]

"CASEN_2941-78-8.htm">2941-78-8
[CAS]

"CASEN_76-25-5.htm">76-25-5
[Formula]

C24H31FO6
[Formula]

C8H9NO2
[Molecular Weight]

434.5
[Molecular Weight]

151.16
[EINECS]

200-948-7
[EINECS]

220-932-3
[RTECS]

TU3920000
[RTECS Class]

Drug; Mutagen; Reproductive Effector; Human Data
[Merck]

12,9728
[Beilstein/Gmelin]

1101527
[Beilstein/Gmelin]

60069
[Beilstein Reference]

5-19-06-00568
[Beilstein Reference]

4-14-00-01357
[Small spills/leaks]

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
[Small spills/leaks]

Vacuum or sweep up material and place into a suitable disposal container.
[Stability]

No data.
[Stability]

Stable at normal temperatures and pressures.
[Incompatibilities]

Strong oxidizing agents.
[Decomposition]

Carbon monoxide, Carbon dioxide, Hydrogen fluoride.
[Decomposition]

Carbon monoxide, oxides of nitrogen, carbon dioxide.