| [Fire Fighting] Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire. | |
| [Ingestion] Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended. | |
| [Inhalation] If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention. | |
| [Skin] Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse. | |
| [Eyes] If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention. | |
| [Storage] Keep in airtight container. | |
| [Handling] Use in hood. Wear protective equipment. Do not raise dust. | |
| [Personal Protection] Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots. | |
| [Respirators] None is normally required. If needed, a NIOSH/MSHA aproved air supplied respirator or dust respirator is advised. | |
| [Exposure Effects] Irritation. Possible allergic reation to dust. May cause dryness of mouth, increased thirst, irregular heartbeat, mood changes, muscle cramps, pain, nausea, vomiting, tiredness, weakness, weak pulse. | |
| [Appearance] White to yellowish-white crystalline powder. Odorless. | |
| [Solubility in water] Slightly soluble | |
| [Melting Point] 179 | |
| [pKa/pKb] 4.43 (pKb) | |
| [Usage] Therap cat (vet): diuretic. | |
| [Product Name] Chlorthalidone | |
| [Synonyms] 1-keto-3-(3'-Sulfamyl-4'-chlorophenyl)-3-hydroxyisoindoline 2-Chloro-5-(3-hydroxy-1-oxoisoindol-3-yl)benzenesulfonamide 3-Hydroxy-3-[4-chloro-3-sulfamylphenyl]phthalimidine Benzenesulfonamide, 2-chloro-5-(2,3-dihydro-1-hydroxy-3-oxo-1H-isoindol-1-yl)- Demi-Regroton Natriuran | |
| [CAS] 77-36-1 | |
| [Formula] C14H11ClN2O4S | |
| [Molecular Weight] 338.77 | |
| [EINECS] 201-022-5 | |
| [RTECS] DB1556000 | |
| [RTECS Class] Reproductive Effector; Human Data | |
| [Merck] 12,2246 | |
| [Beilstein/Gmelin] 312295 | |
| [Beilstein Reference] 5-22-07-00602 | |
| [Small spills/leaks] Wear approved protective equipment. Vacuum or sweep up spill. Avoid dust creation. Place spillage in appropriate container for disposal. | |
| [Stability] Stable under normal temperatures and pressures. | |
| [Incompatibilities] Strong oxidizing agents. | |
| [Decomposition] Toxic fumes. |
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