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2,2'-Azobis(2-methylpropionitrile)

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[Fire Fighting]

Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes. Extinguishing media: Water spray. Carbon dioxide, dry chemical powder or appropriate foam.
[Ingestion]

If swallowed, wash out mouth with water provided person is conscious. Call a physician immediately.
[Inhalation]

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
[Skin]

In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
[Eyes]

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.
[Storage]

Keep container tightly closed. Store at 2 - 8 C.
[EC Risk Phrase]

R: 23/24/25 46
[EC Safety Phrase]

S: 36/37/39 45 53
[UN (DOT)]

3462
[Personal Protection]

Wear self-contained breathing apparatus, rubber boots, and heavy rubber gloves.
[Respirators]

Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N99 (US) or type P2 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator.
[Exposure Effects]

Toxic. May cause heritable genetic damage. Toxic by inhalation, in contact with skin and if swallowed. Nausea, headache, and vomiting. Reversible liver enzyme abnormalities.
[Appearance]

Very faintly beige powder.
[Solubility in water]

Insoluble
[Melting Point]

217 - 218
[Density]

1.41 g/cm3 (20 C)
[pKa/pKb]

9.38 (pKa)
[Partition Coefficient]

-.67
[Usage]

A cytotoxic polypeptide quinoxaline antibiotic isolated from streptomyces echinatus that binds to dna and inhibits rna synthesis.
[Product Name]

Azodiisobutyrodinitrile
[Synonyms]

Echinomycin A
N-[3,11,13,16,24,26-Hexamethyl-27-methylsulfanyl-2,5,9,12,15,18,22,25-octaoxo-4,17-dipropan-2-yl-8-(quinoxaline-2-carbonylamino)-6,19-dioxa-28-thia-3,10,13,16,23,26-hexazabicyclo[12.12.3]nonacos-21-yl]quinoxaline-2-carboxamide
NSC-526417
Quinomycin A
S-426-S (Lepetit)
[CAS]

"CASEN_512-64-1.htm">512-64-1
[Formula]

C51H64N12O12S2
[Molecular Weight]

1101.27
[RTECS]

JW5250000
[Merck]

12,3545
[Beilstein/Gmelin]

78671
[Beilstein Reference]

4-27-00-09726
[Small spills/leaks]

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
[Stability]

Stable at normal temperatures and pressures.
[Incompatibilities]

Strong oxidizing agents.
[Decomposition]

Oxides of carbon, nitrogen and sulfur.
[Combustion Products]

Emits toxic fumes under fire conditions.
[UN Number]

3462
[Hazard Class]

6.1
[Packing Group]

II