| [Fire Fighting] Extinguish with water, carbon dioxide, dry chemical or foam. Wear NIOSH/MSHA approved, positive pressure SCBA and full protective turn out gear. | |
| [Fire Fighting] Small Fires: Dry chemical, carbon dioxide or water spray. Large Fires: Dry chemical, carbon dioxide, alcohol-resistant foam or water spray. | |
| [Fire Potential] Combustible material: may burn but does not ignite readily. | |
| [Ingestion] Never induce vomiting unless directed by medical personnel. Never give anything by mouth to an unconscious person. Obtain medical assistance. | |
| [Ingestion] Seek medical assistance. | |
| [Inhalation] TOXIC; inhalation, ingestion, or skin contact with material may cause severe injury or death. Effects of contact or inhalation may be delayed. | |
| [Inhalation] Remove to fresh air. Give CPR, oxygen if needed. | |
| [Inhalation] Move victim to fresh air. Apply artificial respiration if victim is not breathing. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Administer oxygen if breathing is difficult. | |
| [Skin] Immediately wash with soap and water. | |
| [Skin] Remove and isolate contaminated clothing and shoes. Immediately flush with running water for at least 20 minutes. For minor skin contact, avoid spreading material on unaffected skin. | |
| [Skin] Contact with molten substance may cause severe burns to skin and eyes. See Inhalation. | |
| [Eyes] Flush with water for 15 minutes. | |
| [Eyes] Immediately flush with running water for at least 20 minutes. | |
| [Eyes] See Inhalation. | |
| [Storage] Keep in a cool, dry location in a tightly closed container when not in use. | |
| [Handling] All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood. | |
| [Ingestion] See Inhalation. | |
| [Inhalation] Excess secretions in the tracheal tree, bronchospasm, and pulmonary edema may occur. | |
| [Skin] Dermatitis, urticaria and reversible alopecia have been reported. | |
| [Eyes] Constriction of the pupil, blurred vision, and excessive secretions in the nose and throat may be present. | |
| [Ingestion] Cramping, abdominal pain, hyperperistalsis, vomiting, and diarrhea have been described. | |
| [Hazards] When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards. | |
| [EC Risk Phrase] R 20/21/22 | |
| [EC Safety Phrase] S 23 36/37 | |
| [UN (DOT)] 2810 | |
| [Personal Protection] Plastic/rubber gloves, safety goggles and disposable coveralls. | |
| [Personal Protection] Wear appropriate protective gloves, clothing and goggles. | |
| [Respirators] Wear positive pressure self-contained breathing apparatus (SCBA). | |
| [Respirators] Half face, negative pressure air purifying, dust/mist/fume efficiency filter respirator. Supplied air, full facepiece respirator. | |
| [Exposure Effects] Abnormally low blood pressure may occur from peripheral actions. However, elevated blood pressure may also be seen secondary to the anxiety resulting from the effects on other organ systems. Likewise, bradyarrhythmias are common from the antimyasthenics, but rapid heart rate may occur secondary to the anxiety resulting from the effects on other organ systems. Respiratory rate may be increased in patients with airway compromise. seizures and coma have been described; profound weakness and muscle fasciculations may also occur. In less severe cases, headache, dizziness, and dysarthria may occur. Parkinsonian-like symptoms have been reported during therapeutic use of pyridostigmine. | |
| [Appearance] White or practically white, crystalline powder. Agreeable odor. | |
| [Solubility in water] Freely soluble | |
| [Melting Point] 154 - 155 | |
| [Boiling Point] 88 (25 torr) | |
| [Density] 0.9613 g/cm3 (20 C) | |
| [Usage] Medication. | |
| [Refractive Index] 1.48 (20 C) | |
| [Product Name] Mestinon | |
| [Synonyms] (1-Methylpyridin-1-ium-3-yl) N,N-dimethylcarbamate bromide 2-((1-Methylethyl)thio)ethanol 2-Propan-2-ylsulfanylethanol 3-(Dimethylcarbamyloxy)-1-methylpyridinium bromide 3-Hydroxy-1-methylpyridinium bromide dimethylcarbamate Kalymin Mestinon | |
| [CAS] "CASEN_101-26-8.htm">101-26-8 | |
| [CAS] "CASEN_40811-49-2.htm">40811-49-2 | |
| [Formula] C5H12OS | |
| [Formula] C9H13BrN2O2 | |
| [Molecular Weight] 120.22 | |
| [Molecular Weight] 261.12 | |
| [EINECS] 202-929-9 | |
| [EINECS] 255-090-6 | |
| [RTECS] UU5270000 | |
| [RTECS Class] Drug; Reproductive Effector; Human Data | |
| [Merck] 12,8161 | |
| [Beilstein/Gmelin] 1697233 | |
| [Beilstein/Gmelin] 3764573 | |
| [Beilstein Reference] 4-01-00-02432 | |
| [Beilstein Reference] 4-21-00-00415 | |
| [Small spills/leaks] ELIMINATE all ignition sources. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS. | |
| [Small spills/leaks] Scoop/shovel material into a suitably labeled drum. Secure drum cover and move container to a safe holding area. | |
| [Stability] Stable at normal temperatures and pressures in in a tightly sealed container. | |
| [Decomposition] Oxides of carbon, oxides of nitrogen, hydrogen bromide and brominated compounds. | |
| [Combustion Products] Fire may produce irritating, corrosive and/or toxic gases. | |
| [UN Number] 2810 |
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