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Rapamycin

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[Fire Fighting]

Suitable extinguishing agents: water spray, carbon dioxide, dry chemical powder or foam. Protective equipment: wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
[Storage]

Store solid and solutions at -20 ºC
[Inhalation]

If inhaled, remove to fresh air; if breathing is difficult, give oxygen; if breathing stops, give artificial respiration
[Skin]

Flush with copious amounts of water; remove contaminated clothing and shoes; call a physician
[Eyes]

Check for and remove contact lenses and flush with copious amounts of water; assure adequate flushing by separating the eyelids with fingers; call a physician
[Ingestion]

Wash out mouth with copious amounts of water; call a physician
[Personal Protection]

Protective clothing, heavy rubber gloves, chemical safety goggles.
[Respirators]

NIOSH/MSHA-approved respirator.
[Exposure Effects]

Potent immunosuppresent; may cause irritation to eyes, skin, mucous membranes.
[Appearance]

White to off-white powder.
[Solubility in water]

Insoluble
[Melting Point]

183 - 184
[Density]

1.18 g/cm3
[pKa/pKb]

10.40 (pKa)
[Partition Coefficient]

3.58
[Usage]

Tool for immunochemistry.
[Product Name]

Sirolimus
[Synonyms]

(-)-Rapamycin
Antibiotic AY-22989
AY-22989
NSC-226080
SILA-9268A
Sirolimus
[CAS]

"CASEN_53123-88-9.htm">53123-88-9
[Formula]

C51H79NO13
[Molecular Weight]

914.19
[RTECS]

VE6250000
[Merck]

12,8288
[Beilstein/Gmelin]

5848501
[Beilstein Reference]

6-27
[Small spills/leaks]

Absorb solutions with finely-powdered liquid-binding material (diatomite, universal binders); decontaminate surfaces and equipment by scrubbing with alcohol.
[Stability]

Stable if stored as directed.
[Incompatibilities]

Strong oxidizing agents.