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Acitretin

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[Flash Point]

180
[Fire Fighting]

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
[Fire Potential]

May burn but does not ignite readily.
[Ingestion]

If swallowed, wash out mouth with water provided person is conscious. Call a physician immediately.
[Inhalation]

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
[Skin]

In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
[Eyes]

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.
[Storage]

Keep tightly closed. Store at 2-8 C
[Inhalation]

May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
[Skin]

Causes skin irritation. May be harmful if absorbed through the skin.
[Eyes]

Causes eye irritation.
[Ingestion]

May be harmful if swallowed.
[Hazards]

Emits toxic fumes under fire conditions.
[EC Risk Phrase]

61 36/38 50/53
[EC Safety Phrase]

53 37/39 45 60 61
[UN (DOT)]

3077
[Personal Protection]

Compatible chemical-resistant gloves. Chemical safety goggles.
[Respirators]

Government approved respirator.
[Exposure Effects]

Toxic. Dangerous for the environment. May cause harm to the unborn child. Irritating to eyes and skin. Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
[Appearance]

White powder.
[Solubility in water]

Insoluble
[Melting Point]

219 - 220
[Boiling Point]

521
[Vapor Pressure]

1E-11 (25 C)
[pKa/pKb]

4.79 (pKa)
[Heat Of Vaporization]

83.6 kJ/mol
[Usage]

Used to treat severe psoriasis. Only used when other treatments prove ineffective.
[Product Name]

Etretin
[Synonyms]

9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid
Neotigason
Soriatane
[CAS]

"CASEN_55079-83-9.htm">55079-83-9
[Formula]

C21H26O3
[Molecular Weight]

326.44
[EINECS]

259-474-4
[RTECS]

RA8460000
[RTECS Class]

Drug; Reproductive Effector; Human Data
[Merck]

12,114
[Beilstein/Gmelin]

2158933
[Beilstein Reference]

6-10
[Small spills/leaks]

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
[Stability]

Stable at normal temperatures and pressures.
[Incompatibilities]

Strong oxidizing agents.
[Decomposition]

Carbon monoxide, Carbon dioxide.
[Combustion Products]

Fire may produce irritating, corrosive and/or toxic gases.
[UN Number]

3077
[Hazard Class]

9
[Packing Group]

III