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gamma-Butyrolactone

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[Flash Point]

100-101
[Autoignition]

455
[Fire Fighting]

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
[Upper exp. limit]

15.6
[Lower exp. limit]

2.7
[Fire Potential]

This chemical is combustible.
[Ingestion]

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
[Inhalation]

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
[Skin]

Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
[Eyes]

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
[Storage]

Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightly closed.
[Handling]

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
[Inhalation]

May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
[Skin]

May cause skin irritation.
[Eyes]

May cause eye irritation.
[Ingestion]

May cause digestive tract disturbances. The toxicological properties of this substance have not been fully investigated. May be harmful if swallowed.
[EC Risk Phrase]

R 22 36
[EC Safety Phrase]

S 26 39
[Personal Protection]

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
[Respirators]

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
[Exposure Effects]

Significant respiratory depression may occur in comatose patients. Low heart rate with increases or decreases in blood pressure may be anticipated. the primary effect is dose-related CNS depression; amnesia and hypotonia after 10 mg/kg, somnolence, drowsiness, dizziness, and euphoria after 20 to 30 mg/kg, and coma after 50 to 70 mg/kg.
[Poison Class]

4
[Appearance]

Oily liquid. Pleasant odor.
[Solubility in water]

Very soluble
[Melting Point]

-44
[Boiling Point]

204
[Vapor Pressure]

3.2 (25 C)
[Density]

1.1286 g/cm3 (20 C)
[Partition Coefficient]

-.64
[Heat Of Vaporization]

54.4 kJ/mol
[Heat Of Combustion]

-2011 kJ/mol
[Usage]

Intermediate in synth of polyvinylpyrrolidone, dl-methionine, piperidine, phenylbutyric acid, thiobutyric acids, solvent for polyacrylonitrile, cellulose acetate, methyl methacrylate polymers, polystyrene, constituent of paintermediate removers, textile aids, drilling oils.
[Vapor Density]

3
[Refractive Index]

1.4348 (20 C)
[Product Name]

BLO
[Synonyms]

1,2-Butanolide
1,4-Butanolide
1,4-Lactone
Butyric acid lactone
gamma-Lactone
Oxolan-2-one
[CAS]

"CASEN_96-48-0.htm">96-48-0
[Formula]

C4H6O2
[Molecular Weight]

86.09
[EINECS]

202-509-5
[RTECS]

LU3500000
[RTECS Class]

Tumorigen; Drug; Mutagen; Reproductive Effector; Primary Irritant
[Merck]

13,1596
[Beilstein/Gmelin]

105248
[Beilstein Reference]

5-17-09-00007
[EC Class]

harmful, irritant
[Small spills/leaks]

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Provide ventilation.
[Disposal Code]

1
[Stability]

Stable under normal temperatures and pressures.
[Incompatibilities]

Strong oxidizing agents - strong acids - strong bases - strong reducing agents.
[Decomposition]

Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
[HS Code]

2932 29 80