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Ribonuclease A

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[Fire Fighting]

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Non-combustible, substance itself does not burn but may decompose upon heating to produce irritating, corrosive and/or toxic fumes. Extinguishing media: Substance is noncombustible; use agent most appropriate to extinguish surrounding fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
[Ingestion]

Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
[Inhalation]

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration.
[Skin]

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
[Eyes]

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
[Storage]

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Deep freeze (below -20 C).
[Handling]

Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
[Ingestion]

May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
[Inhalation]

May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
[Skin]

May cause skin irritation. May cause erythema, and edema with crusting and scaling.
[Eyes]

May cause eye irritation.
[Personal Protection]

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
[Respirators]

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
[Appearance]

White to off-white powder.
[Usage]

Biochemical research. Catalytic form of rna.
[Product Name]

Alkaline ribonuclease
[Synonyms]

Alkaline ribonuclease
E.C. 2.7.7.16
E.C. 3.1.4.22
Gigantin
Pancreatic ribonuclease
RNase A
[CAS]

9001-99-4
[EINECS]

232-646-6
[RTECS]

RF0760000
[RTECS Class]

Mutagen
[Beilstein/Gmelin]

NA
[Small spills/leaks]

Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.
[Incompatibilities]

Oxidizing agents.
[Stability]

Stable at room temperature in closed containers under normal storage and handling conditions.
[Decomposition]

Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.