| [Fire Fighting] Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Extinguishing media: Substance is noncombustible; use agent most appropriate to extinguish surrounding fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam. | |
| [Ingestion] Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. | |
| [Inhalation] Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration. | |
| [Skin] Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. | |
| [Eyes] Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. | |
| [Storage] Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Refrigerator (approx 4 C). | |
| [Handling] Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. | |
| [Inhalation] May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Inhalation of high concentrations may result in bronchospasm. | |
| [Skin] May cause skin irritation. May cause erythema, and edema with crusting and scaling. | |
| [Eyes] May cause eye irritation. | |
| [Ingestion] May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated. | |
| [Personal Protection] Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. | |
| [Respirators] A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use. | |
| [Exposure Effects] Reproductive effects have been reported in animals. | |
| [Appearance] White powder. | |
| [Usage] Proteolytic inhibitor in radioimmunoassays of polypeptide hormones. | |
| [Product Name] Aprotinin | |
| [Synonyms] Bovine pancreatic trypsin inhibitor Bovine trypsin inhibitor Kunitz protease inhibitor Trypsin inhibitor Trypsin inhibitor, pancreatic basic Zymofren | |
| [CAS] 9087-70-1 | |
| [Formula] C284H432N84O79S7 | |
| [Molecular Weight] 6511.53 | |
| [EINECS] 232-994-9 | |
| [RTECS] YN5080000 | |
| [RTECS Class] Reproductive Effector | |
| [Merck] 12,796 | |
| [Beilstein/Gmelin] NA | |
| [Small spills/leaks] Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation. | |
| [Incompatibilities] Oxidizing agents. | |
| [Stability] Stable at room temperature in closed containers under normal storage and handling conditions. | |
| [Decomposition] Carbon monoxide, oxides of nitrogen, oxides of sulfur, irritating and toxic fumes and gases, carbon dioxide. |
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