[Flash Point] 129 | |
[Fire Fighting] Extinguish with carbon dioxide, dry chemical powder or appropriate foam. Water spray. Wear self-contained breathing apparatus and protective clothing to prevent contact with the skin and eyes. | |
[Storage] Store in original container in a cool dark place. | |
[Inhalation] Remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen. Seek medical attention. | |
[Skin] Immediately wash skin with soap and copious amounts of water for at least 15 minutes. If irritation persists, seek medical attention. | |
[Eyes] Immediately flush eyes with copious amounts of water for at least 15 minutes. Seek medical advice. | |
[Ingestion] If swallowed, wash out mouth with water, provided person is conscious. Seek medical advice. | |
[Personal Protection] Wear self-contained breathing apparatus, rubber boots & heavy rubber gloves. | |
[Solubility in water] Insoluble | |
[Boiling Point] 289 | |
[Vapor Pressure] 0.0022 (25 C) | |
[Density] 1.392 g/cm3 (20 C) | |
[pKa/pKb] 11.45 (pKa) | |
[Partition Coefficient] 1.95 | |
[Heat Of Vaporization] 52.9 kJ/mol | |
[Usage] Used in active moderate to severe rheumatoid arthritis and psoriatic arthritis. | |
[Product Name] Leflunomide | |
[Synonyms] 4-Isoxazolecarboxamide, 5-methyl-N-(4-(trifluoromethyl)phenyl)- 5-Methylisoxazole-4-carboxylic acid (4-trifluoromethyl)anilide 5-Methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazolecarboxamide Arava HWA-486 | |
[CAS] "CASEN_75706-12-6.htm">75706-12-6 | |
[Formula] C12H9F3N2O2 | |
[Molecular Weight] 270.20999999999998 | |
[RTECS] NY2354200 | |
[Merck] 12,10407 | |
[Small spills/leaks] Sweep-up/absorb in suitable material, place in a container and hold for disposal. Avoid raising dust. Ventilate area and wash spill site after pickup is complete. | |
[Combustion Products] Emits toxic fumes under fire conditions. |