| [Fire Fighting] Extinguish with carbon dioxide, dry chemical powder or appropriate foam. Water spray. Wear self-contained breathing apparatus and protective clothing to prevent contact with the skin and eyes. | |
| [Storage] Store in original container in a cool dark place. | |
| [Inhalation] Remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen. Seek medical attention. | |
| [Skin] Immediately wash skin with soap and copious amounts of water for at least 15 minutes. If irritation persists, seek medical attention. | |
| [Eyes] Immediately flush eyes with copious amounts of water for at least 15 minutes. Seek medical advice. | |
| [Ingestion] If swallowed, wash out mouth with water, provided person is conscious. Seek medical advice. | |
| [Personal Protection] Wear self-contained breathing apparatus, rubber boots & heavy rubber gloves. | |
| [Solubility in water] Slightly soluble | |
| [Vapor Pressure] 3.5E-11 (25 C) | |
| [Density] 1.97 g/cm3 (20 C) | |
| [pKa/pKb] 15.29 (pKa) | |
| [Partition Coefficient] -1.15 | |
| [Usage] Used for the treatment of refractory anaplastic astrocytoma -- a type of cancerous brain tumor. | |
| [Product Name] Temozolomide | |
| [Synonyms] 3,4-Dihydro-3-methyl-4-oxoimidazo(5,1-d)-1,2,3,5-tetrazine-8-carboxamide 8-Carbamoyl-3-methylimidazo(5,1-d)-1,2,3,5-tetrazin-4(3H)-one Imidazo(5,1-d)(1,2,3,5)tetrazine-8-carboxamide, 3,4-dihydro-3-methyl-4-oxo M & B 39831 MB-39831 Methazolastone | |
| [CAS] "CASEN_85622-93-1.htm">85622-93-1 | |
| [Formula] C6H6N6O2 | |
| [Molecular Weight] 194.15 | |
| [RTECS] NJ5927050 | |
| [Merck] 12,9289 | |
| [Beilstein/Gmelin] 5547136 | |
| [Small spills/leaks] Sweep-up/absorb in suitable material, place in a container and hold for disposal. Avoid raising dust. Ventilate area and wash spill site after pickup is complete. | |
| [Combustion Products] Emits toxic fumes under fire conditions. |
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