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Milnacipran hydrochloride (101152-94-7)

Identification
Name:Milnacipran hydrochloride
Synonyms:Cyclopropanecarboxamide,2-(aminomethyl)-N,N-diethyl-1-phenyl-, monohydrochloride, (1R,2S)-rel- (9CI);Milnacipran HCl;Cyclopropanecarboxamide, 2-(aminomethyl)-N,N-diethyl-1-phenyl-,monohydrochloride, cis-;Dalcipran;F 2207;Ixel;Cyclopropanecarboxamide,2-(aminomethyl)-N,N-diethyl-1-phenyl-, hydrochloride (1:1), (1R,2S)-rel-;Toledomin;
CAS:101152-94-7
Molecular Formula: C15H23ClN2O
Molecular Weight: 282.80892
InChI: InChI=1S/C15H22N2O.ClH/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12;/h5-9,13H,3-4,10-11,16H2,1-2H3;1H/t13-,15+;/m1./s1
Molecular Structure: (C15H23ClN2O) Cyclopropanecarboxamide,2-(aminomethyl)-N,N-diethyl-1-phenyl-, monohydrochloride, (1R,2S)-rel- (9CI)...
Properties
Transport:UN 2811
Water Solubility:19 mg/mL in water
Solubility:19 mg/mL in water
Appearance:White crystalline powder
Biological Activity: Orally active 5-HT and noradrenalin re-uptake inhibitor (SNRI) (IC 50 values are 203 and 100 nM respectively) that displays no affinity at a range of other receptors. Causes adaptive changes to α 1 -adrenergic and 5-HT 2A serotonergic systems when administered repeatedly. Exhibits antidepressive and antinociceptive activities in vivo .
Storage Temperature: 2-8°C
Color: white
Usage:Antidepressant
Safety Data
Hazard Symbols Xn: Harmful