| Identification |
| Name: | Medetomidine hydrochloride |
| Synonyms: | 4-[1-(2,3-DIMETHYLPHENYL)ETHYL]-1H-IMIDAZOLE HYDROCHLORIDE;MEDETOMIDINE HCL;1H-Imidazole, 4-1-(2,3-dimethylphenyl)ethyl-, monohydrochloride;4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole Monohydrochloride;Domitor;Metomidine;MPV 785;Zalopine |
| CAS: | 106807-72-1 |
| Molecular Formula: | C13H17ClN2 |
| Molecular Weight: | 236.74 |
| Molecular Structure: |
![(C13H17ClN2) 4-[1-(2,3-DIMETHYLPHENYL)ETHYL]-1H-IMIDAZOLE HYDROCHLORIDE;MEDETOMIDINE HCL;1H-Imidazole, 4-1-(2,3-d...](https://img.guidechem.com/structure/106807-72-1.gif) |
| Properties |
| Biological Activity: | Potent, highly selective α 2 -adrenoceptor agonist (K i values are 1.08 and 1750 nM for α 2 - and α 1 -adrenoceptors respectively). Displays greater selectivity over α 1 -adrenoceptors than clonidine and UK 14,304 (1620-, 220- and 300-fold respectively). Inhibits twitch response in electrically stimulated mouse vas deferens (pD 2 = 9.0). Active in vivo ; displays hypotensive, bradycardic, sedative, anxiolytic, hypothermic and analgesic effects. |
| Usage: | a2-Adrenergic aginist. Sedative; analgesic |
| Safety Data |
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