| Identification |
| Name: | Propanoic acid,3-[[[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]- |
| Synonyms: | Propanoicacid, 3-[[[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]-,(E)-; L 660711; MK 571 |
| CAS: | 115104-28-4 |
| Molecular Formula: | C26H27 Cl N2 O3 S2 |
| Molecular Weight: | 537.07 |
| InChI: | InChI=1/C26H27ClN2O3S2.Na/c1-29(2)24(30)12-14-33-26(34-15-13-25(31)32)20-5-3-4-18(16-20)6-10-22-11-8-19-7-9-21(27)17-23(19)28-22;/h3-11,16-17,26H,12-15H2,1-2H3,(H,31,32);/q;+1/p-1/b10-6+; |
| Molecular Structure: |
![(C26H27ClN2O3S2) Propanoicacid, 3-[[[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]...](https://img1.guidechem.com/chem/e/dict/181/115104-28-4.jpg) |
| Properties |
| Flash Point: | 384.6°C |
| Boiling Point: | 712.3°Cat760mmHg |
| Density: | 1.327g/cm3 |
| Biological Activity: | Potent CysLT 1 (LTD 4 ) leukotriene receptor inverse agonist (EC 50 = 1.3 nM). Antagonizes LTD 4 -induced contractions of guinea pig trachea and ileum (pA 2 values are 9.4 and 10.5 respectively). Also inhibitor of multidrug resistance protein-1 (MRP1) mediated transport; in vitro augments the effects of cytotoxic agents on malignant cells. |
| Flash Point: | 384.6°C |
| Usage: | A receptor antagonist for the treatment of respiratory diseases |
| Safety Data |
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