Identification |
Name: | (-)-Lobeline Hydrochloride |
Synonyms: | Lobeline hydrochloride; 2-(6-(2-hydroxy-2-phenethyl)-1-methyl-2-piperidyl)acetophenone hydrochloride; Lobeline HCL |
CAS: | 134-63-4 |
EINECS: | 205-150-2 |
Molecular Formula: | C22H27NO2?HCl |
Molecular Weight: | 373.92 |
InChI: | InChI=1/C22H27NO2.ClH/c1-23-19(15-21(24)17-9-4-2-5-10-17)13-8-14-20(23)16-22(25)18-11-6-3-7-12-18;/h2-7,9-12,19-21,24H,8,13-16H2,1H3;1H/t19-,20+,21+;/m0./s1 |
Molecular Structure: |
|
Properties |
Transport: | UN 1544 |
Flash Point: | 247.5°C |
Boiling Point: | 485.6°Cat760mmHg |
Density: | g/cm3 |
Refractive index: | -57.5 ° (C=1, H2O) |
Solubility: | 1 G DISSOLVES IN 40 ML WATER, 12 ML ALC; VERY SOL IN CHLOROFORM |
Appearance: | White to off-white solid |
Packinggroup: | III |
Biological Activity: | High affinity nicotinic receptor ligand, with a K i value of 4.4 nM in rat brain. |
Flash Point: | 247.5°C |
Color: | white to off-white |
Usage: | A neuronal nicotinic acetylcholine receptor agonist. A respiratory stimulant |
Safety Data |
Hazard Symbols |
T:Toxic
|
|
|