Methanesulfonamide,N-[2-[4-[3-[4-amino-5-chloro-2-[(3,5-dimethoxyphenyl)methoxy]phenyl]-3-oxopropyl]-1-piperidinyl]ethyl]-,hydrochloride (1:1) (167710-87-4)

Identification
Name:	Methanesulfonamide,N-[2-[4-[3-[4-amino-5-chloro-2-[(3,5-dimethoxyphenyl)methoxy]phenyl]-3-oxopropyl]-1-piperidinyl]ethyl]-,hydrochloride (1:1)
Synonyms:	Methanesulfonamide,N-[2-[4-[3-[4-amino-5-chloro-2-[(3,5-dimethoxyphenyl)methoxy]phenyl]-3-oxopropyl]-1-piperidinyl]ethyl]-,monohydrochloride (9CI); RS 39604
CAS:	167710-87-4
Molecular Formula:	C26H36 Cl N3 O6 S . Cl H
Molecular Weight:	627.02
InChI:	InChI=1/C26H36ClN3O6S.ClH/c1-34-20-12-19(13-21(14-20)35-2)17-36-26-16-24(28)23(27)15-22(26)25(31)5-4-18-6-9-30(10-7-18)11-8-29-37(3,32)33;/h12-16,18,29H,4-11,17,28H2,1-3H3;1H
Molecular Structure:
Properties
Flash Point:	405.5°C
Boiling Point:	746.9°C at 760 mmHg
Biological Activity:	A potent and selective 5-HT 4 antagonist, with a pK i of 9.1 at 5-HT 4 receptors in guinea pig striatal membranes and greater than 1000-fold selectivity over 5-HT 1A, 2C, 3 and D 1 , D 2 , M 1 , M 2 , AT 1, B 1 and α 1C receptors. The ketone group gives RS 39604 a relatively long half life; it is also orally active and so suitable for in vivo studies.
Flash Point:	405.5°C
Safety Data