Trimethylsulfoxonium iodide (1774-47-6)

With the CAS registry number 1774-47-6, Trimethyl sulphoxonium iodide is also named as Sulfonium, trimethyl-, iodide, oxide. The product's categories are iodonium sulfonium & oxonium compounds; sulfonium compounds; sulfur compounds (for synthesis); synthetic organic chemistry; sulfonium / sulfoxonium compounds; organic building blocks; sulfur compounds. It is white to light yellow crystalline powder which is sensitive to light. When heated to decomposition it emits toxic vapors of SO_x and I^-.

The other characteristics of this product can be summarized as:?(1)H-Bond Donor: 0; (2)H-Bond Acceptor: 2; (3)Rotatable Bond Count: 0; (4)Exact Mass: 219.941879; (5)MonoIsotopic Mass: 219.941879; (6)Topological Polar Surface Area: 18.1; (7)Heavy Atom Count: 6; (8)Complexity: 53.

Uses of?Trimethyl sulphoxonium iodide: It is mainly used for synthesis of fluconazole. And it also can be used in?organic synthesis. For example: 1.It reacts with?1-cyclohex-1-enyl-ethanone to get 1-acetylbicyclo[4.1.0]heptane. This reaction needs reagent?NaH and solvent?dimethylsulfoxide. The yield is 42%.



2.It also can react with?adamantan-2-one?to obtain?Adamantan-2-spiro-oxiran. This reaction needs reagent?NaOH?and solvent?propan-2-ol by heating. The reaction time is?1 hours. The yield is 85%.

When you are using this chemical, please be cautious about it as the following:
It is harmful if swallowed. And it is irritating to eyes, respiratory system and skin.?In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?If you want to contact this product, you must wear suitable protective clothing, suitable gloves and eye/face protection.

People can use the following data to convert to the molecule structure.
1. SMILES: [I-].O=[S+](C)(C)C;
2. InChI: InChI=1/C3H9OS.HI/c1-5(2,3)4;/h1-3H3;1H/q+1;/p-1.

The following are the toxicity data which has been tested.

With the CAS registry number 1774-47-6, Trimethyl sulphoxonium iodide is also named as Sulfonium, trimethyl-, iodide, oxide. The product's categories are iodonium sulfonium & oxonium compounds; sulfonium compounds; sulfur compounds (for synthesis); synthetic organic chemistry; sulfonium / sulfoxonium compounds; organic building blocks; sulfur compounds. It is white to light yellow crystalline powder which is sensitive to light. When heated to decomposition it emits toxic vapors of SO_x and I^-.

The other characteristics of this product can be summarized as:?(1)H-Bond Donor: 0; (2)H-Bond Acceptor: 2; (3)Rotatable Bond Count: 0; (4)Exact Mass: 219.941879; (5)MonoIsotopic Mass: 219.941879; (6)Topological Polar Surface Area: 18.1; (7)Heavy Atom Count: 6; (8)Complexity: 53.

Uses of?Trimethyl sulphoxonium iodide: It is mainly used for synthesis of fluconazole. And it also can be used in?organic synthesis. For example: 1.It reacts with?1-cyclohex-1-enyl-ethanone to get 1-acetylbicyclo[4.1.0]heptane. This reaction needs reagent?NaH and solvent?dimethylsulfoxide. The yield is 42%.



2.It also can react with?adamantan-2-one?to obtain?Adamantan-2-spiro-oxiran. This reaction needs reagent?NaOH?and solvent?propan-2-ol by heating. The reaction time is?1 hours. The yield is 85%.

When you are using this chemical, please be cautious about it as the following:
It is harmful if swallowed. And it is irritating to eyes, respiratory system and skin.?In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?If you want to contact this product, you must wear suitable protective clothing, suitable gloves and eye/face protection.

People can use the following data to convert to the molecule structure.
1. SMILES: [I-].O=[S+](C)(C)C;
2. InChI: InChI=1/C3H9OS.HI/c1-5(2,3)4;/h1-3H3;1H/q+1;/p-1.

The following are the toxicity data which has been tested.