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amiloride hydrochloride hydrate (2016-88-8)

Identification
Name:amiloride hydrochloride hydrate
Synonyms:Amiloride Hydrochloride; Amiloride HCl
CAS:2016-88-8
EINECS: 217-958-2
Molecular Formula: C6H8ClN7O?HCl
Molecular Weight: 229.62702
InChI: InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15)
Molecular Structure: (C6H8ClN7O?HCl) Amiloride Hydrochloride; Amiloride HCl
Properties
Transport:UN 2811
Density:2.11 g/cm3
Stability:No data.
Water Solubility:H2O: 50 mg/mL, clear, yellow-green
Solubility:H2O: 50 mg/mL, clear, yellow-green
Appearance:Light yellow solid.
Specification:

??Amiloride hydrochloride , its cas register number is 2016-88-8. It also can be called?Amiloride HCl ; Amiloride chloride ; CCRIS 5959 ; UNII-FZJ37245UC?; N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide monohydrochloride ; Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-, monohydrochloride ; Pyrazinecarboxamide, N-amidino-3,5-diamino-6-chloro-, monohydrochloride . It is a?Crystalline solid or very light yellow powder. It?insoluble in water.?However,?it is probably combustible.
Symptoms of exposure to Amiloride hydrochloride (CAS NO.2016-88-8) include headache, weakness, fatigue, back, chest, neck, shoulder or extremity pain; nausea, anorexia, vomiting, abdominal pain, hyperkalemia, paresthesias, shock, dizziness, coughing, shortness of breath, depression, nervousness, flaccid paralysis of the extremities, bradycardia, flatulence, skin rash, gas pain, constipation and dyspnea.

Packinggroup: II
HS Code: 29339980
Biological Activity: Na + channel blocker. Defines the I 2A -amiloride sensitive and I 2B -amiloride insensitive imidazoline binding sites. Also inhibits TRPP3 channels.
Storage Temperature: Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Color: yellow
Usage:

Sodium channel blocker. Diuretic.

Safety Data
Hazard Symbols T:Toxic
 

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