Identification |
Name: | sodium dichloroacetate |
Synonyms: | Dichloroacetic acid sodium salt |
CAS: | 2156-56-1 |
EINECS: | 218-461-3 |
Molecular Formula: | C2HCl2NaO2 |
Molecular Weight: | 150.92 |
InChI: | InChI=1/C2H2Cl2O2.Na/c3-1(4)2(5)6;/h1H,(H,5,6);/q;+1/p-1 |
Molecular Structure: |
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Properties |
Transport: | 2811 |
Flash Point: | 194°Cat760mmHg |
Boiling Point: | 194°Cat760mmHg |
Density: | g/cm3 |
Stability: | Stable under normal temperatures and pressures. |
Water Solubility: | soluble in cold water |
Appearance: | White powder. |
Biological Activity: | Inhibitor of mitochondrial pyruvate dehydrogenase kinase (PDK). Shifts pyruvate metabolism from glycolysis and lactate production to glucose oxidation in the mitochondria. Induces mitochondrial-dependent apoptosis and reverses the inhibition/downregulation of K V 1.5 channels in cancer but not normal cells. Decreases tumor growth in vitro and in vivo . |
Flash Point: | 194°Cat760mmHg |
Storage Temperature: | Store in a cool, dry place. Store in a tightly closed container. |
Sensitive: | Moisture Sensitive |
Safety Data |
Hazard Symbols |
Xi:Irritant
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