| Identification | |
| Name: | SB 408124 |
| Synonyms: | SB 408124 |
| CAS: | 288150-92-5 |
| Molecular Formula: | C19H18F2N4O |
| Molecular Weight: | 356.37 |
| InChI: | InChI=1/C19H18F2N4O/c1-11-8-17(15-9-12(20)10-16(21)18(15)22-11)24-19(26)23-13-4-6-14(7-5-13)25(2)3/h4-10H,1-3H3,(H2,22,23,24,26) |
| Molecular Structure: |  |
| Properties | |
| Flash Point: | 214°C |
| Boiling Point: | 430.3°Cat760mmHg |
| Density: | 1.371g/cm3 |
| Refractive index: | 1.697 |
| Solubility: | DMSO: ~24 mg/mL |
| Biological Activity: | Selective non-peptide orexin OX 1 receptor antagonist (K b values are 21.7 and 1405 nM for human OX 1 and OX 2 receptors respectively). Blocks orexin-A induced grooming following oral administration in vivo . |
| Flash Point: | 214°C |
| Storage Temperature: | 2-8°C |
| Color: | olive-green |
| Safety Data | |
| Hazard Symbols |
Xi: Irritant
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