| Identification | |
| Name: | Procarbazine hydrochloride |
| Synonyms: | Benzamide,N-(1-methylethyl)-4-[(2-methylhydrazino)methyl]-, monohydrochloride (9CI);p-Toluamide, N-isopropyl-a-(2-methylhydrazino)-, monohydrochloride (8CI);1-Methyl-2-[p-(isopropylcarbamoyl)benzyl]hydrazine hydrochloride;2-[p-(Isopropylcarbamoyl)benzyl]-1-methylhydrazine hydrochloride;IBZ;Ibenzmethyzin hydrochloride;Ibenzmethyzine hydrochloride;MBH;MIHhydrochloride;Matulane;N-Isopropyl-p-(2-methylhydrazinomethyl)benzamidehydrochloride;N-Isopropyl-a-(2-methylhydrazino)-p-toluamide hydrochloride;NCI-C 01810;NSC 77213;Nathulane;Natulan;Natulan hydrochloride;Natulanar;PCB hydrochloride;Ro 4 6467/1;Ro 4-6467;Benzamide,N-(1-methylethyl)-4-[(2-methylhydrazinyl)methyl]-, hydrochloride (1:1); |
| CAS: | 366-70-1 |
| EINECS: | 206-678-6 |
| Molecular Formula: | C12H19N3O.HCl |
| Molecular Weight: | 257.80 |
| InChI: | InChI=1/C12H19N3O.ClH/c1-9(2)15-12(16)11-6-4-10(5-7-11)8-14-13-3;/h4-7,9,13-14H,8H2,1-3H3,(H,15,16);1H |
| Molecular Structure: | ![(C12H19N3O.HCl) Benzamide,N-(1-methylethyl)-4-[(2-methylhydrazino)methyl]-, monohydrochloride (9CI);p-Toluamide, N-i...](https://img1.guidechem.com/chem/e/dict/180/366-70-1.jpg) |
| Properties | |
| Melting Point: | 223ºC |
| Flash Point: | 148.9ºC |
| Boiling Point: | 384.6ºC at 760 mmHg |
| Stability: | No data. |
| Water Solubility: | >=10 G/100 ML AT 21.5 ºC |
| Solubility: | >=10 g/100 mL at 21.5 ºC |
| Appearance: | white to pale yellow crystalline powder |
| Specification: |
Procarbazine hydrochloride (CAS NO.366-70-1) can also be called as N-(1-methylethyl)-4-((2-methylhydrazino)methyl)benzamide hydrochloride ; Procarbazine hcl ; Procarbazine hydrochloride ; Chlorhydratede1-methyl2p(isopropylcarbamoyl)benzyl-hydrazine ; 1-(P-isopropylcarbamoylbenzyl)-2-methylhydrazinehydrochloride ; 1-Methyl-2-(p-isopropylcarbamoylbenzyl)hydrazinehydrochloride ; 1-Methyl-2-p-(isopropylcarbamyol)benzohydrazinehydrochloride ; 2-(P-(isopropylcarbamoyl)benzyl)-1-methylhydrazinehydrochloride . |
| Report: |
NTP 10th Report on Carcinogens. IARC Cancer Review: Group 2A IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 327.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 26 ,1981,p. 311.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 26 ,1981,p. 311.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . NCI Carcinogenesis Bioassay (ipr); Clear Evidence: mouse, rat NCITR* National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-19 ,1979. ; (ipr); Clear Evidence: mouse, rat RRCRBU Recent Results in Cancer Research. 52 (1975),1. . EPA Genetic Toxicology Program. |
| Flash Point: | 148.9ºC |
| Storage Temperature: | Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage. |
| Usage: | Antineoplastic |
| Safety Data | |
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