2-Propanol,1,1,1-trifluoro- (374-01-6)

The 1,1,1-Trifluoropropan-2-ol is an organic compound with the formula C₃H₅F₃O. The IUPAC name of this chemical is 1,1,1-trifluoropropan-2-ol. With the CAS registry number 374-01-6, it is also named as 1-Methyl-2,2,2-trifluoroethanol. The product's categories are Alcohols; C2 to C6; Oxygen Compounds.

Physical properties about 1,1,1-Trifluoropropan-2-ol are: (1)ACD/LogP: 0.66; (2)ACD/LogD (pH 5.5): 0.66; (3)ACD/LogD (pH 7.4): 0.66; (4)ACD/BCF (pH 5.5): 1.86; (5)ACD/BCF (pH 7.4): 1.86; (6)ACD/KOC (pH 5.5): 54.29; (7)ACD/KOC (pH 7.4): 54.29; (8)#H bond acceptors: 1; (9)#H bond donors: 1; (10)#Freely Rotating Bonds: 1; (11)Polar Surface Area: 9.23 Å²; (12)Index of Refraction: 1.312; (13)Molar Refractivity: 17.89 cm³; (14)Molar Volume: 92.3 cm³; (15)Polarizability: 7.09×10^-24cm³; (16)Surface Tension: 17.6 dyne/cm; (17)Density: 1.235 g/cm³; (18)Flash Point: 38.8 °C; (19)Enthalpy of Vaporization: 36.01 kJ/mol; (20)Boiling Point: 67 °C at 760 mmHg; (21)Vapour Pressure: 109 mmHg at 25°C.

Preparation: this chemical can be prepared by trifluoroisopropyl fluorosulfite. This reaction will need reagent H₂O. The reaction time is 10 hours with reaction temperature of 100 °C. The yield is about 95%.

Uses of 1,1,1-Trifluoropropan-2-ol: it can be used to produce (2.2.2-Trifluor-1-methyl-aethyl)-p-toluolsulfonat. It will need reagent aq. NaOH and solvent acetone.

When you are using this chemical, please be cautious about it as the following:
It is highly flammable. Besides, this chemical is irritating to eyes, respiratory system and skin. When you are using it, wear suitable protective clothing, keep away from sources of ignition - No smoking, and take precautionary measures against static discharges. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1)SMILES: FC(F)(F)C(O)C
(2)InChI: InChI=1/C3H5F3O/c1-2(7)3(4,5)6/h2,7H,1H3
(3)InChIKey: GILIYJDBJZWGBG-UHFFFAOYAG
(4)Std. InChI: InChI=1S/C3H5F3O/c1-2(7)3(4,5)6/h2,7H,1H3
(5)Std. InChIKey: GILIYJDBJZWGBG-UHFFFAOYSA-N