| Identification | |
| Name: | MMPIP HYDROCHLORIDE |
| Synonyms: | 6-(4-METHOXYPHENYL)-5-METHYL-3-(4-PYRIDINYL)-ISOXAZOLO[4,5-C]PYRIDIN-4(5H)-ONE HYDROCHLORIDE;MMPIP HYDROCHLORIDE;MMPIP |
| CAS: | 479077-02-6 |
| Molecular Weight: | 0 |
| Molecular Structure: | ![() 6-(4-METHOXYPHENYL)-5-METHYL-3-(4-PYRIDINYL)-ISOXAZOLO[4,5-C]PYRIDIN-4(5H)-ONE HYDROCHLORIDE;MMPIP H...](https://img.guidechem.com/structure/479077-02-6.gif) |
| Properties | |
| Biological Activity: | Potent allosteric mGlu 7 -selective receptor antagonist. Inhibits agonist-induced intracellular calcium mobilization and cAMP accumulation (IC 50 values are 26 and 610 nM). Displays intrinsic activity; increases forskolin-induced cAMP accumulation in the absence of an agonist (IC 50 = 15 nM), indicating inverse agonist activity. |
| Safety Data | |
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