| Identification | |
| Name: | Pregn-4-ene-3,20-dione,11,21-dihydroxy-, (11b)- |
| Synonyms: | Corticosterone(8CI);11,21-Dihydroxyprogesterone;11-Hydroxycorticoaldosterone;11b,21-Dihydroxypregn-4-ene-3,20-dione;11b,21-Dihydroxyprogesterone;17-Deoxycortisol;4-Pregnene-11b,21-diol-3,20-dione;Kendall's compound B;NSC 9705;Reichstein's substance H; |
| CAS: | 50-22-6 |
| EINECS: | 200-019-6 |
| Molecular Formula: | C21H30O4 |
| Molecular Weight: | 346.51 |
| InChI: | InChI=1/C21H30O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h9,14-17,19,22,24H,3-8,10-11H2,1-2H3/t14-,15-,16+,17-,19+,20-,21-/m0/s1 |
| Molecular Structure: |  |
| Properties | |
| Melting Point: | 179-183 °C(lit.) |
| Flash Point: | 288°C |
| Boiling Point: | 529.2°Cat760mmHg |
| Density: | 1.21g/cm3 |
| Stability: | Stable, but light sensitive. Incompatible with strong oxidizing agents. |
| Refractive index: | 1.575 |
| Water Solubility: | Stability Stable, but light sensitive. Incompatible with strong oxidizing agents. Toxicology May cause sensitization by skin contact. Toxicity data (The meaning |
| Solubility: |
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| Appearance: | white to light yellow powder |
| Specification: |
Corticosterone ,its cas register number is 50-22-6. It also can be called 11b,21-Dihydroxypregn-4-ene-3,20-dione ; (11b)-11,21-Dihydroxypregn-4-ene-3,20-dione ; 11b,21-Dihydroxyprogesterone ; 11b,21-Dihydroxy-4-pregnene-3,20-dione and Pregn-4-ene-3,20-dione, 11,21-dihydroxy-, (11beta)- . It is a 21 carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands. Corticosterone (CAS NO.50-22-6) is a main glucocorticoid, involved in immune reactions, regulation of fuel, and stress responses. |
| Biological Activity: | Endogenous glucocorticoid that acts as an agonist at glucocorticoid and mineralocorticoid receptors. |
| Flash Point: | 288°C |
| Storage Temperature: | Store at RT |
| Color: | Colorless solid Light-tan powder Light brown crystalline solid |
| Usage: | Glucocorticoid; an intermediate in the biosynthesis of aldosterone, isolated from the adrenal cortex. |
| Safety Data | |
| Hazard Symbols | |
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