| Identification | |
| Name: | 5,8,11,14-Eicosatetraenoicacid, 2-hydroxy-1-(hydroxymethyl)ethyl ester, (5Z,8Z,11Z,14Z)- |
| Synonyms: | 5,8,11,14-Eicosatetraenoicacid, 2-hydroxy-1-(hydroxymethyl)ethyl ester, (all-Z)-;2-Arachidonylglycerol;2-Monoarachidonoylglycerol; |
| CAS: | 53847-30-6 |
| Molecular Formula: | C23H38O4 |
| Molecular Weight: | 378.54542 |
| InChI: | InChI=1S/C23H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(26)27-22(20-24)21-25/h6-7,9-10,12-13,15-16,22,24-25H,2-5,8,11,14,17-21H2,1H3/b7-6-,10-9-,13-12-,16-15- |
| Molecular Structure: |  |
| Properties | |
| Transport: | UN 1648 3 |
| Density: | 0.992 g/cm3 |
| Refractive index: | 1.507 |
| Appearance: | Liquid |
| Specification: | usageEng:2-Arachidonoylglycerol is a major endocannabinoid, which can inhibit synaptic transmission by presynaptic cannabinoid CB1 receptors. It plays an inhibitory role in the bombesin-induced activation of central adrenomedullary outflow in rats. Safety Statements:26-36/37 26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 36/37:Wear suitable protective clothing and gloves |
| Biological Activity: | Endogenous cannabinoid ligand that acts as a potent agonist at GPR55 (EC 50 values are 3, 519 and 618 nM at GPR55, CB 1 and CB 2 respectively; K i values are 472 and 1400 nM at CB 1 and CB 2 respectively). Found in the brain at concentrations 1000-fold higher than that of anandamide. |
| Storage Temperature: | −20°C |
| Usage: | 2-Arachidonoylglycerol is a major endocannabinoid, which can inhibit synaptic transmission by presynaptic cannabinoid CB1 receptors. It plays an inhibitory role in the bombesin-induced activation of central adrenomedullary outflow in rats. |
| Safety Data | |
| Hazard Symbols |
Xn: Harmful
F: Flammable
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